The prime directive prohibits all spaceships and members of starfleet any interference* in the default evolution of alien cultures and societies. In the daily use, this directive stands above the safety of spaceships and members of starfleet. Losses will be tolerated as long as they are needed to accomplish the directive.
(*) Under "interference" means explicitly to give any hints about the universe, other planets or other civilisations to societies progressing in technological development. This goes only for pre-warp societies.
2nd Directive: Protection of intelligent alien lifeforms.
Under no circumstances, even not to protect his/her own life or that of his/her crew, an officer is allowed to do harm to an intelligent lifeform. A break of this directive is only tolerated if otherwise the prime directive would be offended.
3rd Directive: Protection of intelligent alien lifeforms
It is an officer's duty to use all devices under his or her command to protect the life of intelligent lifeforms, even if this means to endanger him/herself, or his/her ship. If an intelligent lifeform is harmed due to an officer acting or not acting this is treated equal as a violation of the 2nd directive.
4th Directive: Following superior's orders
An officer shall follow a superior's order at his or her best, unless these would result in a violation of the Prime, 2nd or 3rd directive.
5th Directive: Protection of the Federation
An officer shall use all his power to protect the safety of Starfleet, the United Federation of Planets, it's memberworlds and their representatives unless this would violate directives 1 to 4.
6th Directive: Self-destruct while diseased
If the entire personnel on board a ship is deceased or would become incapable of acting during a period of 24 hours the ship should be destroyed to prevent other lifeforms or ships from being contaminated.
7th Directive: Quarantine on Talos IV
Repealed. [Formerly: Under which circumstances ever, even if in a case of emergency, a Federation ship is not allowed to visit Talos IV. Ignoring this directive will lead to a death penalty.]
8th Directive: Prohibition of entering Romulan territory
No Federation ship is allowed to enter the Romulan Star Empire, unless this is justified by directive 1 to 5. Directive was modified in 2297: "Klingon territory" removed
9th Directive: Prohibition of visiting planets and starsystems under quarantine
No Federation ship is allowed to visit a planet or starsystem that was put under quarantine by the United Federation of Planets or the Starfleet, unless this necessary by directive 1 to 5.
10th Directive: Responsibility and prosecution
An Starfleet officer is responsible under laws and orders of the United Federation of Planets, it's memberworlds and their representatives, including Starfleet. He or she is subject to any prosecution by authorities under the named laws.
11th Directive: Respecting contracts and aiding contract partners
A Starfleet officer shall respect contracts and bondings made by the United Federation of Planets and their memberworlds and provide any aid requested by the signers of those contracts or bondings.
12th Directive: Reacting to approaching ships without communication
While approaching a ship while no communication has been made or isn't possible, safety procedures are to be held.
13th Directive: Prohibition of informing hostile lifeforms
While wearing a starfleet uniform an officer is prohibited to give informations or equivalent aid to the Federation's enemies or to groups which represent a danger for the Federation, it's memberworlds or their representives.
14th Directive: Modest acting
An officer shall not act improper or indecent or show an offensive or modesting behaviour against other lifeforms.
15th Directive: Protecting commanding officers
No commanding officer is allowed to enter a zone of danger or an area not to be completely free of danger without an armed escort.
16th Directive: Conviction on board
An officer can be convicted by at least three commanding officers for a crime violating Starfleet directives or Federational laws.
17th Directive: Taking over the command in absence of the commanding officer
In absence of the commanding officer, if he or she gets killed or if he or she is misfit or incapable the highest officer by rank takes over command, even if he or she does not belong to the standard personnel on board.
18th Directive: Prohibition of mutiny (see also 4th directive)
An officer is not allowed to start or to take part in a mutiny against his or her superiors. Mutiny will be judged as violation of the 4th directive.
19th Directive: Recall from duty
An officer can be recalled from duty at any time if he or she is judged to be incapable of fulfilling his duty for medical or psychological reasons by the ship's medical officer or by two commanding officers.
20th Directive: Help and offensive actions against Federation and other starships
Federation ships shall give any aid and support requested by registered private or commercial ships from the the United Federation of Planets, and they are allowed to take disciplinic or offensive actions against illegal acting ships or hostile ships operating in federational territory.
21st Directive: Prohibition of transporting illegal materials and weapons; confiscation of smuggled goods.
A Federationship is not allowed to transport any substance or freight, which is classified as illegal by the Federartion, nor an illegal quantity of any susbtance or freight, nor any weapon not registered by the Federation's tradeoffice. Destructive lifeforms also fall under this directive. Federation ships are allowed to search a ship under suspect of smuggling and to confiscate any found smuggled goods.
22nd Directive: Help for planets stuck in evolution and for planets under foreign control (see also: Prime directive)
At contact with a planet who does not make any progress in its evolution or which is under foreign control an officer is allowed to make changes within the social structure with the aim to lead the planet on a course towards a technological civilisation. Any misuse of this directive is regarded as violating the prime directive.
23rd Directive: Destruction of intelligent life (see also: 2nd Directive)
The destruction of one or more intelligent lifeforms is only allowed to prevent a violation of the primedirective, and also only if there is no other way to prevent this violation. Any misuse of this directive is regarded as violation of the 2nd directive.
24th Directive: Destruction of the entire intelligent life on a planet (see also: Prime directive and 23rd directive)
The destruction of the entire intelligent life on the surface of a planet is only allowed, if the inhabitants of the named planet have severely violated the prime directive. Such an action can only be ordered by a commanding officer with captain's rank or higher. This officer is solely responsible for this action. Any misuse of this directive is regarded as violating the prime directive.