If GH was a cartoon...
Katherine Bell would be Kenny from South Park.

You can poison her, shoot her, push her off a parapet, it doesn't matter.

She'll be back, alive and kicking.
Mac Scorpio would be Shaggy, and his favorite detective, Lt. Marcus Taggert, would be Scooby Doo.

Together, these two investigators will blunder through numerous investigations,

except in the cartoon world, they would always get the bad guys.
Cesar Faison would be Gargamel from the Smurfs:

constantly threatening "I'll get you, if it's the last thing I ever do!"

but never actually doing anything.
Laura Spencer would be Smurfette:

she has terrible taste in clothes, and big pouffy blonde hair, and a tendency to get herself into trouble.

Not to worry though, there's always a male Smurf ready to come to her rescue!
Bobbie Spencer would be Jessica Rabbit.

She's got a damn ugly face and her eyes are way too big for her head,

but men don't notice because they're too busy checking out her cleavage.
Stefan Cassadine would be Animal from the Muppet Babies.

He's got the outward appearance of a force to be reckoned with,

but when it's time for action, he always proves to be as soft and defenceless as a baby.

Hannah Scott would be Garfield.

All he ever thinks about is lasagne and sleeping.

All Hannah ever thinks about is dessert and "going to bed". Close enough.
Lesley-Lu Spencer would be Maggie Simpson from The Simpsons.

The only difference: Maggie Simpson gets more lines, and has a better wardrobe.
Edward Quartermaine would be Mr. Burns from The Simpsons.

I don't think I need to explain this one.