| Act 48 | The Wolf Revived |
| Act 49 | Cruel as a Wolf |
| Act 50 | Despicable Acts |
| Act 51 | Confrontation |
| Act 52 | The Wolf Bares His Fangs |
| Act 53 | A Call and Answer |
| Act 54 | The One Who Can Stop Them |
| Act 55 | A Request from Okubo Toshimichi |
| Act 56 | May 14, 1878 - Morning |
| Act 57 | May 14, 1878 - Evening |
- Begins: Kenshin remembers fighting the Shinsen Gumi ten years ago in Kyoto
- Ends: Kenshin's departure (the sayonara scene with Kaoru)
- Important Happenings:
- Introduction of the Shinsen Gumi
- Appearance of Saitou, Saitou vs. Sanosuke
- Kenshin vs. Akamatsu
- Kenshin vs. Saitou, revert to Battousai
- Introduction of Shishio and the Juppon Gatana, Okubo's request to Kenshin to fight Shishio
- Okubo's assassination by Soujirou
- Kenshin says goodbye to Kaoru, leaves for Kyoto