PATENTS (4 found on 15th February, 2005):
1. THERAPEUTIC AND PROPHYLACTIC TREATMENT OF AGING AND DISORDERS OF AGING IN HUMANS
Patent number: WO03070167
Publication date: 2003-08-28
Inventor: RODRIGUEZ VICTORIO C (US)
Applicant: RODRIGUEZ VICTORIO C (US)
Abstract of WO03070167
A method for the treatment and prophylaxis of conditions of aging in humans, such conditions of aging associated with a decreased presence of cell-specific carbonic anhydrase enzymes in the brain, such as conditions associated with chronic neurodegenerative conditions including dementia such as Alzheimer's disease, which method includes the administering over an extended period of time, ranging from 6 months to 5 years, of a pharmaceutically effective, non-toxic amount of a compound that increases the presence of cell-specific carbonic anhydrase enzymes in the brain. That compound may be the cell-specific carbonic anhydrase enzyme, a compound that when absorbed by the body reacts or dissociates to form the cell-specific carbonic anhydrase enzyme, or a compound that promotes the natural generation of the cell-specific carbonic anhydrase enzyme within the body.
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Also published as: WO03070167 (A3) ,
EP1482952 (A3),
EP1482952 (A2)
Cited documents: EP0680960,
WO0193744,
XP004181015,
XP002968991
See also: Bioorg Med Chem. 2002 Feb;10(2):425-32
2. Patent number: WO03075930
Publication date: 2003-09-18
Inventor: ALKON DANIEL L [US]; SUN MLAO-KUN [US]
Applicant: BLANCHETTE ROCKEFELLER NEUROSC [US];; ALKON DANIEL L [US];; SUN MLAO-KUN [US]
Abstract of WO03075930
The present invention relates to the combination of a methylxanthine and a carbonic anhydrase activator to provide synergistic effects. The invention further relates to the improved/enhanced cognitive ability of individuals, particularly those suffering from various disorders, such as Alzheimer's Disease, stroke, hypoxia, general dementia, ADHD, mental retardation, and "sun down" syndrome.
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Also published as: US6821979 (B2), US2003171385 (A1)
Cited documents: US5554601, WO0062812, XP002963905
3. Patent number: US6821997
Publication date: 2004-11-23
Inventor: RODRIGUEZ VICTORIO C [US]
Abstract of US6821997
A method for the treatment and prophylaxis of conditions of aging in humans, such conditions of aging associated with a decreased presence of cell-specific carbonic anhydrase enzymes in the brain, such as conditions associated with chronic neurodegenerative conditions including dementia such as Alzheimer's disease, which method includes the administering over an extended period of time, ranging from 6 months to 5 years, of a pharmaceutically effective, non-toxic amount of a compound that increases the presence of cell-specific carbonic anhydrase enzymes in the brain. That compound may be the cell-specific carbonic anhydrase enzyme, a compound that when absorbed by the body reacts or dissociates to form the cell-specific carbonic anhydrase enzyme, or a compound that promotes the natural generation of the cell-specific carbonic anhydrase enzyme within the body.
4. Patent number: US2004253223
Publication date: 2004-12-16
Inventor: RODRIGUEZ VICTORIO C [US]
Abstract of US2004253223
A method for the treatment and prophylaxis of conditions of aging in humans, such conditions of aging associated with a decreased presence of one or more cell-specific carbonic anhydrase enzymes. Such conditions include chronic neurodegenerative conditions including dementia such as Alzheimer's disease. The method comprises administering to the patient a pharmaceutically effective, non-toxic amount of a compound that increases the presence of one or more cell-specific carbonic anhydrase enzymes whose levels are reduced in the patient. Such compound may be the cell-specific carbonic anhydrase enzyme, a compound that when absorbed by the body reacts or dissociates to form the cell-specific carbonic anhydrase enzyme, or a compound that promotes the natural generation of the cell-specific carbonic anhydrase enzyme within the body.