Restaurants:

Old Town: Casa de Bandini, Casa de Pico,
Old Town Mexican Cafe (2489 San Diego Ave. Call 619-297-4330)
Mission Beach: (on the Pacific - watch for the "green flash" at sunset)
TD Hayes, Rusty Pellican, Suskas

Gaslamp Quarter: Croce's
Kearny Mesa: 94 Aero Squadron - 163 Balboa, Asian - Balboa and Convoy
Other: Miguels, Top of the Market, Rainwater
La Jolla: PF Chang, Palamino, Crab Catcher, Tutto Mare - Executive Dr.
Dining Links
1-Fun-Trip-2
San Diego's Best
Fodor's
San Diego Insider

Coronado
An island (although it is connected by a small strip of land 8 mi. south) across the bay from San Diego is accessible via a bridge or ferry. On the San Diego side is the Ferry Landing Marketplace. Coronado's Specialty Bay front Shopping & dining Center. Unique Shops & Galleries, Bike Rentals, Restaurants & Fun Eateries.
On the Pacific side is the Hotel Del Coronado, or just 'the Dell'. For over 100 years, the Hotel Del Coronado has been host to Presidents, world dignitaries, movie stars and even it's own ghost. It is considered one of North America's most beautiful resorts.

Other Links:
University of Calif. San Diego - Map.
San Diego State University - Map.
The University of San Diego
Pacific Beach
Mission Beach
La Jolla
SAIC San Diego Locations