Fat distribution can influence a person's risk of disease. Fat carried around the waist and in the abdominal area, characterized by the "apple shape", is associated with an increased risk for many medical problems such as heart disease, cancer, high blood pressure, and diabetes. Fat that is mostly distributed around the buttocks and thighs is associated with a lower risk of developing these diseases.
People respond differently to appetite suppressant medications, and some people experience more weight loss than others. Some obese patients using medication lose more than 10 percent of their starting body weight- an amount of weight loss that may reduce risk factors for obesity - related diseases, such as high blood pressure or diabetes.
Over the short term, weight loss in obese individuals may reduce a number of health risks. Studies looking at the effects of appetite suppressant medication treatment on obesity-related health risks have found that some agents lower blood pressure, blood cholesterol, triglycerides (fats) and decrease insulin resistance (the body's inability to use blood sugar) over the short term. Long-term studies are currently being done to determine if weight loss from appetite suppressant medications can improve health.
Appetite suppressant medications are not "magic bullets", or a one- shot fix. They cannot take the place of improving one's diet and becoming more physically active. The major role of medications appears to be to help a person stay on a diet and exercise plan to keep off the weight they lose.
Many people are motivated to diet by wanting to be thin and attractive like the models we see everywhere - on TV and in magazines. What is far more important is that a leaner body reduces the risk for certain diseases.