HEALTH SCIENCES INSTITUTE

Members Alert for January 2001 Vol. 5, No 7

Billion-dollar drug company nearly squashes astounding
research on natural cancer killer

Colon and breast cancer conquered with miracle tree from the Amazon
found to be 10,000 times stronger than chemotherapy

Since our inception in 1996, Health Sciences Institute has scoured the world to find cutting-edge treatments few people have access to or have even heard about. And sometimes, what we uncover startles even the medical mavericks on our board.

Two months ago, we learned about an astounding cancer-fighting tree from the Amazon
that has literally sent shock waves through the HSI network

Today, the future of cancer treatment and the chances of survival look more promising than ever. There's a healing tree that grows deep within the Amazon rain forest in South America that could literally change how you, your doctor, and possibly the rest of the world think about curing cancer. With extracts from this powerful tree, it may now be possible to...

Through a series of confidential communications involving a researcher from one of America's largest pharmaceutical companies, this ancient tree's anticancerous properties have recently come to light. Although not yet tested in human trials, the tree has been studied in more than 20 laboratory tests since the 1970s, where it's been shown to:

So why isn't every health publication extolling the benefits of this treatment? Why hasn't it been made widely available throughout the natural-medicine community? And, if it's only half as promising as it appears to be, why isn't every oncologist at every major hospital insisting on using it on all his patients? Especially when you consider that since the early 1990s, extensive independent research--including research by one of today's leading drug companies and by the National Cancer Institute--confirms that the tree's chemical extracts attack and destroy cancer cells with lethal precision.


Graviola is 10,000 times stronger in killing colon cancer
than Adriamycin, a commonly used chemotherapeutic drug.

The answer to these difficult questions can only be explained by recounting a disturbing story we recently uncovered. More than anything else we've reported on this year, the story of this Amazon cancer treatment reinforces the need for groups like HSI and illustrates how easily our options for medical treatment are controlled by money and power.

News of this amazing tree was nearly lost forever

A confidential source, whose account we've been able to independently confirm, revealed that a billion-dollar drug company in the United States tried for nearly seven years to synthesize two of the tree's most powerful anticancerous chemicals. In the early 1990s, behind lock and key, this well-known drug giant began searching for a cure for cancer--while preciously guarding their opportunity to patent it and, therefore, profit from it.

Research focused on a legendary healing tree called Graviola. Parts of the tree--including the bark, leaves, roots, fruit, and fruit seeds--had been used for centuries by medicine men and native Indians in South America to treat heart disease, asthma, liver problems, and arthritis. Going on little documented scientific evidence, the company poured money and resources into testing Graviola's anticancerous properties--and they were shocked by the results. Graviola was a cancer-killing dynamo. But that's where the story of Graviola nearly ended.

The pharmaceutical company had a big problem. They'd spent years trying to isolate and create man-made duplicates of two of the tree's most powerful chemicals. But they'd hit a brick wall. They couldn't replicate the original. And they couldn't sell the tree extract itself profitably--because federal law mandates that natural substances can't be patented. That meant the company couldn't protect its profits on the project it had poured millions of dollars and nearly seven years of research into.

As the dream of big profits evaporated, testing on Graviola came to a screeching halt

After seven frustrating years and without the promise of lucrative sales, the company shelved the project and refused to publish its findings in an independent journal. But one responsible researcher struggled with the decision. While understanding the company's goal of profits, he couldn't accept the decision to hide this unique cancer killer from the world. Following his conscience and risking his career, he contacted Raintree Nutrition, a company dedicated to harvesting plants from the Amazon.

As a result, Raintree went into high gear and began to research related studies published on Graviola. They discovered that several other teams in the United States (in addition to that of the drug company) had been testing Graviola in vitro (in test tubes). The results supported the drug company's secret findings; Graviola had been shown to kill cancer cells.

Encouraged by these early laboratory tests, Raintree hired indigenous Indian tribes in Brazil to grow and harvest the tree. They spent a year on research and development and then began offering Graviola in the United States. They also developed a new supplement called N-Tense, which contains 50 percent Graviola as well as smaller amounts of seven other cancer-killing botanical extracts. (See page 4 for more information on N-Tense.)

Health Sciences Institute came across Graviola and Raintree Nutrition a few months ago while researching Chanca Piedra, a natural kidney-stone therapy from the Amazon, that was featured in our September 2000 issue. In the course of our working together, Raintree pointed us toward Graviola. And needless to say, our panel of experts were intrigued by the possibility of this powerful natural cure for cancer.

Graviola hunts down and destroys prostate, lung, breast,
colon, and pancreatic cancers... leaving healthy cells alone

Since November, we've been looking closely into the research to date on Graviola. It appears one of the first scientific references to it in the United States was by the National Cancer Institute (NCI). In 1976, the NCI included Graviola in a plant-screening program that showed its leaves and stems were effective in attacking and destroying malignant cells. But the results were part of an internal NCI report and were, for some reason, never released to the public.1

Since 1976, there have been several promising cancer studies on Graviola. However, the tree's extracts have yet to be tested on cancer patients. No double-blind clinical trials exist, and clinical trials are typically the benchmark mainstream doctors and journals use to judge a treatment's value. Nevertheless, Graviola has been shown to kill cancer cells in vitro in at least 20 laboratory tests that our research has uncovered.

The most recent study, conducted at Catholic University of South Korea earlier this year, revealed that two chemicals extracted from Graviola seeds showed "selective cytotoxicity comparable with Adriamycin" for breast and colon cancer cells. The chemicals targeted and killed malignant breast and colon cells in a test tube--comparable to the commonly used chemotherapy drug Adriamycin.2

Another study, published in the Journal of Natural Products, showed that Graviola is not only comparable to Adriamycin--but dramatically outperforms it in laboratory tests. Results showed that one chemical found in Graviola selectively killed colon cancer cells at "10,000 times the potency of Adriamycin."3


Graviola selectively targets cancer cells leaving healthy cells untouched.
Chemotherapy indiscriminately seeks and destroys all actively
reproducing cells - even normal, healthy ones.

Other promising and ongoing research at Purdue University is supported by a grant from the National Cancer Institute. Purdue researchers recently found that leaves from the Graviola tree killed cancer cells "among six human-cell lines" and were especially effective against prostate and pancreatic cancer cells.4 In a separate study, Purdue researchers showed that extracts from the Graviola leaves are extremely effective in isolating and killing lung cancer cells.5

Perhaps the most significant result of the study cited above from the Catholic University of South Korea, and of each of the others we've found, is that Graviola was shown to selectively target the enemy--leaving all healthy, normal cells untouched. By comparison, chemotherapy indiscriminately seeks and destroys all actively reproducing cells--even normal hair and stomach cells. This is what causes such often-devastating side effects as hair loss and severe nausea. In this respect, Graviola looks to be a promising alternative or supplement to mainstream treatments.

Patient reports show Graviola and N-Tense help eliminate tumors

From a clinical standpoint, Graviola still has a long way to go. Its properties have only been studied in a test tube. That's why it has yet to become widely known and accepted. The unfortunate truth is that without the promise of huge revenues from a synthesized, patented drug, it's unlikely that any pharmaceutical company will invest the hundreds of thousands (even millions) of dollars it would take to conduct the double-blind, placebo-controlled studies on humans. This is the underlying challenge to substantiating most nutritional therapies. Fortunately, Graviola is a natural substance, so we don't have to wait around for the drug companies. And, thanks to one researcher with a conscience, Raintree Nutrition bravely took the initiative in making this promising cure available.

Only a relative handful of doctors and patients in the United States have been using Graviola and the Graviola-rich botanical supplement N-Tense to fight cancer. Still, according to Raintree Nutrition, the combined therapy has produced some incredible results.

One such case history involved an executive at a high-tech company in Texas. Daryl S. came across Raintree when exploring alternative treatments to cure his prostate cancer. A sonogram and biopsy confirmed that Daryl had more than 20 tumors in his prostate. One doctor recommended surgery. But Daryl thought a cure using this common conventional treatment would come at too great a cost. He didn't want to suffer from impotence and incontinence for the rest of his life.

Instead, he agreed to a far less invasive round of hormonal therapy (to shrink the size of his prostate) and began a rigorous supplement regimen that centered around the Graviola-rich supplement N-Tense.

Within two months, Daryl's PSA level had dropped from 4.1 to 0.00. A sonogram and several other gamma-ray tests later confirmed that all the malignant tumors inside his prostate had disappeared.

Seven years of silence broken

We are continuing to work with Raintree and others conducting ongoing research on Graviola. As more scientific and anecdotal evidence comes to light, you'll be among the first to hear about it. However, after seven years of silence and hidden research, we felt it irresponsible not to bring this to you now.

Grown and harvested by indigenous people in Brazil, Graviola is available in limited supply in the United States and distributed only through Raintree Nutrition. But now, you can be among a select few in the entire country to benefit from Graviola. We encourage you, as always, to consult with your doctor before beginning any new therapy, especially when treating cancer.

You can make tea out of the Graviola leaves, obtain the herb alone in capsule form, or benefit from the power of Graviola combined with seven other immune-boosting herbs in Raintree Nutrition's N-Tense capsules. (See the sidebar on page 4 for more details on N-Tense.)

Graviola leaves are available through Raintree Nutrition at $19 per pound or at $15.00 per 100 capsules. Each capsule contains 700 milligrams. Based on South American traditional therapies, it's recommended you take one to five grams a day. As a dietary supplement, N-Tense should be taken at 6 to 8 capsules daily. You can order 120 capsules for $24.

Graviola and N-Tense are completely natural substances with no side effects apart from possible mild gastrointestinal upset at high dosages (in excess of 5 grams) if taken on an empty stomach.



1. Unpublished data, National Cancer Institute. Anon: Nat Cancer 1st Central Files--(1976)
from Napralert Files, University of Illinois, 1995
2. Bioorg Med Chem 8(1):285-90, 2000
3. J Nat Prod 59(2):100-108, 1996
4. Phytochemistry 49(2):565-71, 1998
5. J. Nat Prod 58(6):902-908, 1995



Graviola fights more than cancer...


While the research on Graviola has focused on its cancer-fighting effect,
the plant has been used for centuries by medicine men in South America to
treat an astonishing number of ailments, including:
hypertension ringworm
influenza scurvy
rashes malaria
neuralgia dysentery
arthritis palpitations
rheumatism nervousness
high blood pressure insomnia
diarrhea fever
nausea boils
dyspepsia muscle spasm
ulcer



Despite the mounting collection of laboratory tests and anecdotal reports about this
cancer-fighting dynamo, Graviola may always remain an underground therapy!

Graviola has yet to be clinically tested on animals or humans. And because Graviola is a natural product, it can't be patented. Without the promise of exclusive sales and high profitability, it will likely never again draw the attention of a major drug company or research lab. So we may never see a double-blind clinical study on the tree that's reported to help defeat cancer.

But there's no doubt about it--the early laboratory tests and anecdotal reports about Graviola are very exciting. And if you've been diagnosed with cancer, you and your doctor should look at all the available treatment options. Graviola may just provide the help you've been looking for that could make all the difference in beating cancer.

Raintree Nutrition can supply you with more information on Graviola and N-Tense. See page 8 for ordering and contact information.

Note: We are carefully tracking the success of Graviola use among our members. Please write to us describing your experiences with this important treatment.

Send to: Graviola Project, Health Sciences Institute, 819 N. Charles St., Baltimore, MD 21201.





SIDEBOX SPREAD 4-5

Unlocking the healing bounty within the Amazon...

The U.S. National Cancer Institute has identified 3,000 plants that are active against cancer cells--70 percent of which are found in the Amazon rainforest.1 Until recently, only shaman, healers, and indigenous tribes held the key to unlocking their extraordinary secrets. Now, thanks to the unrelenting work of leading nutritional researchers, herbalists, and alternative doctors like those in the HSI network, the healing secrets of these plants, such as Graviola, are being uncovered.

In addition to promoting Graviola, Raintree Nutrition has taken the lead in making several other rainforest botanicals available to U.S. practitioners and consumers. They've combined Graviola with seven of these to create a power-packed, immune-boosting formula called N-Tense. Graviola makes up 50 percent of the N-Tense formula, which also consists of smaller amounts of the rainforest botanicals described below. These extracts have been widely used by indigenous people in South America and other tropical regions around the world to heal a wide range of ailments, including indigestion, inflammation, liver and gallbladder disorders, hepatitis, malaria, infection, respiratory problems, and more. And over the last decade, many of them have become popular among alternative physicians. But it's their cytotoxic and immune-boosting potential, as shown in studies, that makes these extracts invaluable in the fight against cancer.

Bitter melon (Momordica charantia)

Over the last decade, most of the research on bitter melon has focused on the vegetable's anti-viral properties. But bitter melon extracts are also being closely studied for their anticancerous properties.

Five of the plant's phytochemicals have been well documented as having cytotoxic properties, meaning they've been shown to both kill and inhibit the growth of cancer cells in vitro. One recent in vitro test conducted by researchers at Seoul National University studied the cytotoxic effects of 100 plants on different cell lines in the body. According to their results, the bitter melon extract showed the "strongest" ability to kill and retard the proliferation of cancer cells.2

Espinheira Santa (Maytenus illicifolia)

Early scientific research in the 1970s showed that this tree's leaves contain a unique group of chemicals called maytansinoids that display powerful antitumorous properties. Although testing on cancer patients revealed some significant regressions in ovarian carcinoma and some lymphomas, research was discontinued due to the toxicity reported at high dosages. In the 1990s, scientists isolated and synthesized a version of the tree's chemicals showing little to no toxicity to humans. Since then, the tree has been given a second look.

According to one recent study by a research team in Massachusetts, maytansinoid extracts were found to be "100- to 1,000-fold more cytotoxic than anticancer drugs currently in clinical use." Specifically, when combined with a special protein called an antibody that hunts down and kills foreign substances in the body, this chemical extract was found to be highly cytotoxic toward cultured colon cancer cells in vitro and showed "remarkable antitumor efficacy in vivo" (in the body).3

Mullaca (Physalis angulata)

Mullaca's recently identified steroids have garnered the most attention from the scientific community. In several in vivo animal tests and in vitro lab tests, Mullaca's steroids demonstrate powerful immune-system support.

Recent cancer studies indicate Mullaca is capable of killing several different types of malignant cells in vitro. In one study from 1992, Mullaca exhibited strong cytotoxicity against cancerous kidney cells in a test tube. The plant extract was also shown to reduce the size of cancerous tumors in mice with lymphocytic leukemia.4

Vassourinha (Scoparia dulcis)

Much of the recent research on Vassourinha has centered around one powerful phytochemical called scopadulcic acid B (SDB). In a 1993 clinical study, SDB inhibited the growth of tumors in a test tube and in mice.5 Since the mid-1990s, scientists have been trying to synthesize several of Vassourinha's phytochemicals, including SDB, for mainstream use by the pharmaceutical industry.6

Mutamba (Guazuma ulmifolia)

In 1990, a team of Brazilian researchers demonstrated that leaf extracts from the Mutamba tree inhibited the growth of cancer cells in vitro by 97.3 percent. Some of the latest research on Mutamba has focused on the antioxidants found in the bark and leaves and their ability to inhibit the growth of bacteria and pathogens.

Suma (Pfaffia paniculata)

Recent studies on Suma's anticancerous properties look particularly promising. Two of Suma's phytochemicals have been shown to inhibit the growth of tumor cells in vitro, and in the year 2000 a Japanese team of researchers demonstrated that Suma inhibited lymphomas and leukemia in mice.

Cat's Claw (Uncaria tomentosa)

Recent studies indicate that at least six of the Cat's Claw vine's alkaloids can increase the functioning of the immune system by up to 50 percent. This has led to its use around the world by cancer and AIDS patients. Cancer patients who take Cat's Claw in conjunction with traditional cancer therapies have reported fewer side effects than typically associated with chemotherapy and radiation, such as hair loss, weight loss, nausea, secondary infections, and skin problems. Additionally, five of the vine's alkaloids have been shown to inhibit the growth of lymphoma and leukemic cells in vitro.7


Used for centuries by South American medicine men, Graviola and these other botanicals from the Amazon have only recently begun to reveal their secrets in rigorous scientific tests. And their cancer-fighting potential is undeniable. Furthermore, these extraordinary botanicals actually boost your immune system, instead of destroying it, as chemotherapy does. By taking N-Tense, you can support your overall health and mount a powerful, all-natural assault on cancer.



1. Rainforest Facts found at http://www.rain-tree.com/facts.htm
2. Anticancer Res 18(1A):119-24, 1998
3. Proc Natl Acad Sci USA 93(16):8618-23, 1996
4. Anticancer Res 12(3):837-43, 1992
5. Oncology 50(2):100-3, 1993 6. Fitoterapia (61)4:353-355, 1990 7. Anticancer Res 18(5A):3363-8, 1998






MEMBER SOURCE DIRECTORY
GRAVIOLA
Raintree Nutrition, Inc. 10609 Metric Blvd., Suite 101, Austin, TX 78758;
tel(800)780-5902 or (512)833-5006; fax (512)833-5414.
http://www.rain-tree.com/graviolacaps.htm
100 Capsules cost $15.00

N-TENSE (featuring Graviola and seven other rainforest herbs)
Raintree Nutrition, Inc. 10609 Metric Blvd., Suite 101, Austin, TX 78758;
tel(800)780-5902 or (512)833-5006; fax (512)833-5414.
http://www.rain-tree.com/n-tense.htm
120 capsules cost $24.00



This article appeared in the monthly publication of the Health Sciences Institute © Copyrighted, 2001 by
Institute for Health Sciences L.L.C.,
819 N. Charles Street
Baltimore, MD 21201.
(410) 223-2690
subscriberadvocate@agora-inc.com
http://www.hsibaltimore.com/


The Health Sciences Institute is dedicated to uncovering and researching the most urgent advances in modern underground medicine. Whether they come from a laboratory in Malaysia, a clinic in South America, or a university in Germany, our goal is to bring the treatments that work directly to the people who need them. We alert our members to exciting breakthroughs in medicine, show them exactly where to go to learn more, and help them understand how they and their families can benefit from these powerful discoveries.

If you would like to subscribe to the Health Sciences Institute's monthly publication, Members Alert, contact the member services hotline at (800)981-7157 or (978)514-7857.






HSI
HEALTH SCIENCES INSTITUTE



Private access to hidden cures...powerful discoveries...breakthrough treatments...
and urgent advances in modern underground medicine




Page 6




HSI members battle prostate cancer with
herbal complex from the Amazon

It's been called a miracle tree. Indigenous peoples from the Amazon jungle have used the bark, leaves, roots, flowers, fruit, and seed from the graviola tree for centuries to treat heart disease, asthma, liver prob-lems, and arthritis. Scientists from North America learned of the legendary healing tree and, through dozens of in vitro tests, discovered its ability to kill malignant cells of 12 different types of cancer, including colon, breast, prostate, lung, and pancreatic cancer. Laboratory research showed it to be 10,000 times stronger in killing colon cancer cells than Adriamycin, a commonly used chemotherapy drug. And graviola, unlike chemotherapy, can kill cancer cells without harming healthy cells.

Pharmaceutical companies—who couldn't turn a profit on a natural substance that couldn't be patented —shelved their research on graviola. But one company developed the botanical into a supplement called N-Tense. In January 2001, Health Sciences Institute broke the story of this rare and potent cancer-killer, and numerous members have benefitted from it over the past year.

W.R. from Knoxville, Tennessee, had a lot of pain when he urinated and thought he might be passing a kidney stone. He was examined by his doctor and found out he had a PSA of 38. Prostate Specific Antigen (PSA) is a marker for prostate cancer. A level of 0 to 4 is normal. W.R. immediately underwent mainstream treatments and reduced his PSA to 9.8, but it wouldn't drop any further. After one month of using N-Tense, his PSA dropped to 4.5. And after a second month of supplementation, it dropped it to 2.2!

T. U. in Douglas, Ontario, told us about his 76- year-old brother in England who had advanced prostate cancer. Mainstream medical treatments seemed useless, and his doctors gave him a year to live. After reading about N-Tense in the Members Alert, T.U. sent his brother some. After only four days of taking a full dose, his brother's pain vanished. In less than a month, he was in remission—and even his oncologists couldn't explain why. Today he still takes N-Tense to make sure his cancer cells continue to shrink.

It is important to note, however, that not everyone has had a successful experience with N-Tense. J.G. from Cherokee Village, Arkansas, had a PSA of 9 and took N-Tense for a month to try to reduce that level. Instead of dropping, his levels jumped to 29. His doctor gave him two hormone shots, which reduced his PSA to 2.4. He tried N-Tense one more time. His PSA went back up to 9, and J.G. switched to PC-Spes.

And a few people had unexpected experiences with N-Tense. A.C. from Palm Springs, California decided to give the supplement to her Irish wolf-hound, who had osteosarcoma (a type of bone cancer). The veterinarian suggested amputation or chemotherapy (at $1,000 per treatment), both of which were unacceptable options. After treating her dog with flaxseed oil and six capsules of N-Tense per day, the bone cancer disappeared.

For information on ordering N-Tense from an HSI approved source, refer to the Member Source Directory on page 8.

Please note: Several members have asked us about a graviola/ ellagitanin product available online through Greenwood Health Systems, which posted our January 2001 article on its website without our authorization. We are not in any way affiliated with Greenwood and don't know enough about the company or its product to recommend anything from their line.





Page 7


As an anti-cancer supplement, graviola has shown incredible promise, but it has failed to show results against one major condition. It is powerless against leukemia. So Raintree Nutrition, the company that introducedus to graviola with N-Tense, has developed Ntense-2--an anti-cancer formula that may help prevent leukemia relapses by stimulating the immune system.

Ntense-2 contains some of the same ingredients as the original N-Tense, such as the immune system enhancers mullaca and cat's claw. Both products also contain vassourinha, which inhibits tumor growth. In place of graviola, Ntense-2 contains several other natural cancer-fighters that show promise in the battle against leukemia.

Simaruba. The National Cancer Institute has known about simaruba's potent anti-amebic activity for 40 years, but it wasn't until 1978 that in vitro (test tube) research showed that it also contains dehydroglaucarubinone, which significantly inhibits the growth of lymphocytic leukemia.1 Dehydro-glaucarubinone is part of a group of phytochemicals called quassinoids. As research continued, scientists discovered additional quassinoids in simaruba that had antileukemic activity.2 To date, there have been no human studies on this herb, although a few animal studies support the results of the in vitro tests.

Anamu. This plant fights cancer by directly attacking malignant cells.3 According to Raintree Nutrition's web site, research shows it also enhances the immune system by stimulating natural killer cell activity and increasing the production of inter-leukin-2, a protein that further enhances immunity. One of the constituents of anamu is coumarin, which may be a concern for those taking blood-thinning drugs. Coumarin can enhance the effects of blood thinning medications and increase the risk of bleeding.

Brazilian peppertree. Also known as mastic tree and Jesuit's balsam, the Brazilian peppertree is a potent antimicrobial agent which works against a wide range of bacteria and viruses.4 According to Raintree, in vitro tests show it is effective against a specific type of cancer cell, that can be found in cancers of the throat, esophagus, and other areas, in addition to exhibiting general anticancer activity. Researchers have known about the antibacterial properties of the Brazilian peppertree since 1966, when they patented a formula for a topical bactericidal medicine based on an essential oil of the plant.

Ntense-2 is available from Raintree Nutrition, which recommends a dosage of six to 12 capsules a day. Ordering information is in the Member Source Directory on page 8.






Page 8

N-Tense & NTENSE-2, Raintree Nutrition, Inc., 10609 Metric Blvd., Suite 101, Austin, TX 78758;
tel. (800) 780-5902 or (512) 833-5006; fax (512) 833-5414;
120 capsules cost US$24.00 plus S&H; or log on to www.rain-tree.com.





The above article appeared in the monthly publication of the
Health Sciences Institute © Copyrighted, 2002 by
Institute for Health Sciences L.L.C.,
819 N. Charles Street
Baltimore, MD 21201.
http://www.hsibaltimore.com/
subscriberadvocate@agora-inc.com
(410) 223-2690



1