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Graves' ophthalmopathy after surgery and RAI

Br J Surg 1993 Sep;80(9):1134-6
Graves' ophthalmopathy after subtotal thyroidectomy and radioiodine therapy.
Fernandez Sanchez JR, Rosell Pradas J, Carazo Martinez O, Torres Vela E, Escobar Jimenez F, Garbin Fuentes I, Vara Thorbeck R - Department of Surgery, University Hospital, Granada, Spain.


Forty-five patients with Graves' ophthalmopathy were studied prospectively.

Twenty-one patients (42 orbits; group 1) were treated surgically by subtotal thyroidectomy and 24 (48 orbits; group 2) received radioiodine therapy.

All patients underwent tests of thyroid function, ophthalmological examination, and axial and coronal computed tomography before and 12 months after treatment.

Patients in group 1 showed significant improvement in the Feldon score (P < 0.001), in proptosis as estimated by Hertel exophthalmometry (P < 0.001) and in proptosis (P < 0.001), maximum diameter of the medial rectus (P < 0.01), lateral rectus (P < 0.05), superior group (P < 0.05) and inferior rectus (P < 0.001) muscles as estimated by computed tomography.

Patients in group 2 showed significant improvement only in the Feldon score (P < 0.05).

The ophthalmopathy of Graves' disease improves to a greater extent after subtotal thyroidectomy than after radioiodine therapy.

PMID: 8402112, UI: 94005635



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