John Keats was born on October 31, 1795, in London. The oldest of four children, he lost both his parents at a young age. His father, a livery-stable keeper, died when Keats was eight; his mother died of tuberculosis six years later. When Keats was fifteen, Abbey withdrew him from the Clarke School, Enfield, to apprentice with an apothecary-surgeon and study medicine in a London hospital. In 1816 Keats became a licensed apothecary, but he never practiced his profession, deciding instead to write poetry.

Around this time, Keats met Leigh Hunt, an influential editor of the Examiner, who published his sonnets "On First Looking into Chapman's Homer" and "O Solitude." Hunt also introduced Keats to a circle of literary men, including the poets Percy Bysshe Shelley and William Wordsworth. The group's influence enabled Keats to see his first volume, Poems by John Keats, published in 1817.

Keats spent the summer of 1818 on a walking tour in Northern England and Scotland, returning home to care for his brother, Tom, who suffered from tuberculosis. While nursing his brother, Keats met and fell in love with a woman named Fanny Brawne. Writing some of his finest poetry between 1818 and 1819. That same autumn Keats contracted tuberculosis.

In July 1820, he published his third and best volume of poetry, Lamia, Isabella, The Eve of St. Agnes, and Other Poems. The three title poems, dealing with mythical and legendary themes of ancient, medieval, and Renaissance times, are rich in imagery and phrasing.

The fragment "Hyperion" was considered by Keats's contemporaries to be his greatest achievement, but by that time he had reached an advanced stage of his disease and was too ill to be encouraged. He continued a correspondence with Fanny Brawne and--when he could no longer bear to write to her directly--her mother, but his failing health and his literary ambitions prevented their getting married. Under his doctor's orders to seek a warm climate for the winter, Keats went to Rome with his friend, the painter Joseph Severn. He died there on February 23, 1821, at the age of twenty-five, and was buried in the Protestant cemetery.