S25 aka DYS463 null

John McEwan

15^th July 2006

Background

It was noticed by Alister John Marsh that a higher level of nulls existed in DYS463 in some haplogroups and the suspicion was that a SNP existed within this region. Considerable work by Ethnoancestry identified and developed the S25 SNP test. As yet it is unclear whether this SNP is the same as the DYS463 null phenomena. There are several people who claim that a separate SNP in the same region is associated with the so called South West Irish R1b group or Irish III group.

See Ken Nordtvedt’s modal for R1b-Ir3

The same group is a subcluster of R1bSTR49 . It is the separate subgroup/branch between Harvey YX6ND and McConnell HQTRT, near the top of the cluster.

Occurrence

Currently on the R1b SNP table there are 6 S25+ derived individuals. However, 2 R1a individuals are also derived and I1c and an E3b individual are ancestral. Thus it would appear that S25 is at present a poorly defined SNP defining an upper level node in the Y chromosome haplogroup tree.

Summary

S25 is a novel as yet only partially defined SNP.