IB WCS 27

FERTILITY REGULATION

Dr OS Tang

O&G

Wed 18-09-02

IDEAL CONTRACEPTION

  1. 100% effective (>90-95% is already effective)
  2. No ill effects (usually used for years)
  3. Simple and cheap (so all educational levels & social classes can use)
  4. Minimal motivation
  5. Under control of patient (can stop if doesn't want)
  6. Maintenance and supervision easy (ideally, no supervision)
  7. Reversible (eg. Sterilisation: fulfils all criteria except that of reversibility)
  8. No deleterious effects on subsequent conceptions

 

FAILURE RATE

Pregnancy rate per hundred woman year (hwy) (of hundred women that use it in a year's time, how many will get pregnant)

= Total accidental pregnancies x 1200

Total months exposure

[1200 = 12 x 100]

 

CONTRACEPTION: High Failure Rate

(1) COITUS INTERRUPTUS

(2) RHYTHM METHOD

    1. Menses
    2. Dry days (if any - infertile)
    3. Wet mucous days - ovulation - thick mucous or dry days (fertile phase)
    4. Dry days (infertile phase)
    5. Menses (again)

 

CONTRACEPTION: Barrier Methods

(3) CONDOM/ SHEATH

(4) OCCLUSIVE DEVICES

 

CONTRACEPTION: Prevent Implantation

(5) INTRAUTERINE CONTRACEPTIVE DEVICE

    1. Inert e.g. Lippes
    2. Bioactive e.g. copper T or 7 or levonorgestrel IUCD; need renewal every 3-5 years

Advantages of IUD

Inserted during a woman's period (sure that woman is not pregnant)

  1. Simple (must see Dr)
  2. Little motivation (must have check-ups to check IUCD thread present)
  3. Non-coitus-related (cf. condom, diaphragm)
  4. Local effect (even levonorgestrel IUCD)
  5. 90% conceive within 1 year of removal

Mechanism of Action

  1. Inhibition of sperm migration in the upper female genital tract
  2. Inhibition of ovum transport in Fallopian tube
  3. Inhibition of fertilisation
  4. Inhibition of implantation (can be used as post-coital method; causes foreign-body reaction in endometrium)

New Copper IUCD

    1. Lippes loop
    2. Copper 7
    3. China ring: inert
    4. Multiload
    5. Copper T: most common (aka Gynae-T)

Advantages of New Copper IUCDs

  1. Smaller and easier to insert
  2. Less side effects
  3. Lower pregnancy rate: <1/HWY (b/c impregnated with higher copper level)

Levonorgestrel IUCD

Complications of IUCD

  1. Expulsion: once expelled, no contraceptive effect
  2. Bleeding
  3. Pain: during period, foreign body present
  4. Perforation: usually during insertion (inserted too far); can migrate through myometrium into pelvic or peritoneal cavity
  5. Pelvic infection: as with any foreign body (low risk); usually occurs at insertion or change of IUCD
  6. Pregnancy

Bleeding

    1. Increased menstrual flow
    2. Longer periods
    3. Intermenstrual bleeding
    1. Use smaller IUCD or LNG IUCD
    2. May improve after several cycles
    3. NSAID: part of Tx for menorrhagia
    4. Anti-fibrinolytic agents
    5. Oral iron: if anaemic
    6. Remove IUCD

Pregnancy with IUCD in situ

    1. Spontaneous abortion
    2. Septic second-trimester abortion
    3. Premature delivery

IUCD & Ectopic Pregnancy

  1. 1. Does not increase overall risk of ectopic pregnancy
  2. Protects against IU pregnancy better than ectopic
  3. Increased ectopic to intrauterine pregnancy ratio

Pelvic Inflammatory Disease

Contraindications

  1. Women with multiple sexual partners
  2. Active or recent PID
  3. Known or suspected pregnancy
  4. Undiagnosed abnormal vaginal bleeding
  5. Suspected/confirmed genital tract malignancy
  6. Congenital uterine abnormality or fibroids that prevent proper placement: eg. Bicornuate uterus, septum (increased chance of expulsion), uterus didelphys - double-uterine cavity (IUCD in one uterine not effective)

 

CONTRACEPTION: Hormonal Methods (Oral Contraceptives)

(6) MODERN COMBINED ORAL CONTRACEPTIVES (COC)

Mechanism of Action

S/E

Major Complications of OC

COC - Absolute Contraindications

COC - Relative Contraindications (Risks usually outweigh benefits)

Benefits of COC

    1. Mid-cycle pain (suppresses ovulation - cause of mid-cycle pain)
    2. Menstrual irregularity
    3. Pre-menstrual tension and dysmenorrhoea

(7) CONTINUOUS LOW DOSE PROGESTAGENS

(8) DEPOT HORMONAL CONTRACEPTION

Mode of Action

Disadvantages

Advantages

(9) PROGESTOGEN IMPLANTS

 

CONTRACEPTION: Post-Coital

    1. Intercourse unexpected
    2. Rape
    3. Failure of barrier methods
    1. High failure rate
    2. S/E

(10) YUZPE REGIMEN

    1. Method limitation
    2. Other intercourse earlier than 72hr ago
    3. High dosage causes vomiting -> vomit pill out, lost contraceptive efficacy

(11) POST-COITAL INSERTION OF Cu IUCD

Advantages

  1. Highly effective pregnancy rate < 0.1%
  2. Can be used 5 days after intercourse
  3. Continued contraception

Disadvantages

 

ASSESSMENT OF PT SEEKING CONTRACEPTION

 

ABORTION

HK: LEGAL REQUIREMENTS

1st Trimester TOP (Termination of Preg)

  1. Surgical methods: Suction evacuation
  2. Medical method (<9 wks): Mifepristone + PG

Complications of vacuum aspiration

2nd trimester TOP

    1. Drug-related: vomiting, diarrhoea, fever
    2. Haemorrhage
    3. Infection
    4. Uterine rupture and cervical tears

Counselling

 

CONTRACEPTION: Permanent

STERILISATION: FEMALE

Timing

Method

Complications

STERILISATION: MALE

Advantages

Disadvantages

COUNSELLING: Both Sexes