JAMA EBM Series:
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JAMA publishes a series of articles on Evidence-Based
Medicine, known as the
Users' Guides to the Medical Literature.
As of today (2001 Dec 17), there are 32 articles in the series,
and you can find them here.
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JAMA Rational Clinical Exam Series:
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JAMA also publishes the
Rational Clinical Examination
series, whose articles teach evidence-based clinical exams.
Click here to enter.
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Lancet Epidemiology Series:
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Lancet publishes a series of articles on clinical epidemiology
written by D. Grimes and K. Schultz.
As of May 2002, there are 11 articles in the series,
and you can find them here.
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EBM Sessions for MacIntMed Residents:
2003 Feb 12, 3pm | HalfDay on EBM (Dr. G. Guyatt)
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Hu FB, Manson JE, Stampfer MJ, et al.
Diet, Lifestyle, and the Risk of Type 2 Diabetes Mellitus in Women
NEJM 2001 Sep 13; 345(11):790-97.
DMwomen.pdf (112kb)
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Scenarios
Feb12scenario.pdf (48kb)
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2003 Jan 30, 6pm | Dr. S. Yusuf
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The Heart Protection Study (HPS)
Heart Protection Study of cholesterol lowering with simvastatin in 20,536
high-risk individuals: a randomised placebocontrolled trial.
Lancet 2002 Jul 6; 360:7-22.
HPS.pdf (198kb)
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The Antihypertensive and Lipid-Lowering Treatment
to Prevent Heart Attack Trial (ALLHAT)
Major Outcomes in High-Risk Hypertensive Patients Randomized to
Angiotensin-Converting Enzyme Inhibitor or Calcium Channel Blocker
vs Diuretic
JAMA 2002 Dec 18; 288(23):2981-97.
ALLHAT.pdf (288kb)
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2002 Dec 11, pm | HalfDay on EBM (Dr. G. Guyatt)
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Gress TW, Nieto FJ, Shahar E, et al.
Hypertension and antihypertensive therapy as risk factors for
type 2 diabetes mellitus
NEJM 2000 Mar 30; 342(13):905-12.
AntiHTN-DM.pdf
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Scenarios
AntiHTN-DM-Scenario.pdf
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2002 Nov 26, 6pm | Dr. D. Cook & Dr. S. Capes
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Berghe GV, Wouters, P, Weekers F, et al.
Intensive Insulin Therapy in Critically Ill Patients.
NEJM 2001 Nov 8;345(19):1359-67.
InsulinICU.pdf
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Rivers E, Nguyen B, Havstad S, et al.
Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock.
NEJM 2001 Nov 8;345(19):1368-77.
GoalSepsis.pdf
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2002 Sep 25, 3pm | HalfDay on EBM (Dr. G. Guyatt)
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Wells PS, Brill-Edwards P, Stevens P, et al.
A Novel and Rapid Whole-blood Assay for D-Dimer in Patients with
Clinically Suspected Deep Vein Thrombosis.
Circulation 1995;91(8):2184-7.
SimpliRED.pdf
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Scenarios
SimpliRED-Scenarios.pdf
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2002 Sep 5, 6pm | Dr. A. Morris & Dr. G. Guyatt
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Marrie TJ, Lau CY, Wong CJ, et al.
A Controlled Trial of a Critical Pathway for Treatment of Community-Acquired Pneumonia.
JAMA 2000;283:749-55.
CAPtrial.pdf>
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Finch R, Schurmann D, Collins O, et al.
Randomized Controlled Trial of Sequential IV and Oral Moxifloxacin Compared
with Sequential IV and Oral Co-Amoxiclav with or without Clarithromycin in
Patients with Community-Acquired Pneumonia Requiring Initial Parenteral
Treatment
Antimicrob Agents Chemother 2002 Jun;46:1746-54.
CAP.pdf
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2002 Jun 6, 7am | Dr. G. Guyatt (AM Session #8)
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Basic statistics for clinicians: 3. Assessing the effects of treatment: measures of association
CMAJ 1995; 152(3):351-357.
EBMstats3.htm
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Basic statistics for clinicians: 4. Correlation and regression
CMAJ 1995; 152(4):497-504.
EBMstats4.htm
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Example article: PCI-CURE (already posted under Cardiology)
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Example article: TRICC Subgroup (already posted below on Feb 7)
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2002 May 16, 7am | Dr. G. Guyatt (AM Session #7)
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Basic statistics for clinicians: 1. Hypothesis testing
CMAJ 1995; 152(1):27-32.
EBMstats1.htm
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Basic statistics for clinicians: 2. Interpreting study results: confidence intervals
CMAJ 1995; 152(2):169-173.
EBMstats2.htm
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2002 Apr 18, 6pm | Dr. G. Guyatt & Dr. E. Kaminska
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Lipsky PE, Van Der Heijde D, St. Clair EW, et al.
Infliximab and methotrexate in the treatment of rheumatoid arthritis.
NEJM 2000;343:1594-602.
RemicadeRA.pdf
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2002 Apr 10, 7am | Dr. G. Guyatt (AM Session #6)
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Low-Molecular-Weight Heparins Compared with Unfractionated
Heparin for Treatment of Acute Deep Venous Thrombosis:
A Cost-Effectiveness Analysis
Ann Intern Med 1999; 130(10):789-99.
EBM-DVT.pdf (continuation of the Mar 14 Session)
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2002 Mar 14, 7am | Dr. G. Guyatt (AM Session #5)
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Low-Molecular-Weight Heparins Compared with Unfractionated
Heparin for Treatment of Acute Deep Venous Thrombosis:
A Cost-Effectiveness Analysis
Ann Intern Med 1999; 130(10):789-99.
EBM-DVT.pdf
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2002 Feb 7, 6-8pm | Dr. S. Yusuf & Dr. M. Blajchman
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Wu WC, Rathore SS, Wang Y, et al.
Blood transfusion in elderly patients with acute myocardial infarction.
NEJM 2001;345:1230-6.
TransfusionMI.pdf
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Hebert PC, Yetisir E, Martin C, et al.
Is a low transfusion threshold safe in critically ill patients with cardiovascular diseases?
Crit Care Med 2001 Sep;29(2):227-234.
Online via MD Consult
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2002 Jan 9, 7am | Dr. G. Guyatt (AM Session #4)
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Kearon C, Ginsberg JS, Douketis J, et al.
Management of Suspected Deep Venous Thrombosis
in Outpatients by Using Clinical Assessment and
D-Dimer Testing
Ann Int Med 2001 Jul 17; 135(2):108-111.
ddimerDVT.pdf
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2001 Dec 5, 7am | Dr. G. Guyatt (AM Session #3)
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Brophy JM, Joseph L, Rouleau JL.
Beta-Blockers in Congestive Heart Failure:
A Bayesian Meta-Analysis
Ann Int Med 2001 Apr 3; 134(7):550-560.
BBinCHF.pdf
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2001 Nov 21, 7am | Dr. G. Guyatt (AM Session #2)
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Wardlaw JM, Warlow CP, Counsell C.
Systemic review of evidence on thrombolytic
therapy for acute ischemic stroke.
Lancet 1997;350:607-14.
(Unfortunately, the PDF is not available from
Lancet.)
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2001 Nov 5, 6-8pm | Dr. M. Crowther & Dr. D. Cook
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Bernard GR, Vincent E-L, Laterre P-F, et al.
Efficacy and Safety of Recombinant Human
Activated Protein C for Severe Sepsis
NEJM 2001 Mar 8; 344(10):699-709.
APC.pdf
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Warren BL, Eid A, Singer P, et al.
High-Dose Antithrombin III in Severe Sepsis
JAMA 2001 Oct 17; 286(15):1869-78.
AT3.pdf
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2001 Oct 25, 7am | Dr. G. Guyatt (AM Session #1)
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Lau JYW, Sung JJY, Lee KKC, et al.
Effect of Intravenous Omeprazole on Recurrent
Bleeding after Endoscopic Treatment of Bleeding
Peptic Ulcers
NEJM 2000 Aug 3; 343(5):310-316.
Lau.pdf
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