Ohio State Route 146 is a east-west highway across Muskingum County. This runs through the center portion of it. From Zanesville to the Muskingum/Licking County Line it runs along the Licking River. OH St Rt 146 passes through the following highways in Muskingum County. Spratt Freeland Chandlersville Zanesville Nashport OH St Rt 146 is multi-plexed in Muskingum County. Ohio State Route 60, at Zanesville. Ohio State Route 93, at Zanesville. U.S. Rt. 22, at Zanesville. OH St Rt 146 crosses the following highways in Muskingum County. Ohio State Route 284, at Chandlersville. Ohio State Route 313, near Chandlersville. Ohio State Route 60, at Zanesville. Ohio State Route 93, at Zanesville. U.S. Rt. 22, at Zanesville. U.S. Rt. 40, at Zanesville. Ohio State Route 93, at Zanesville. Interstate 70, at Zanesville. Ohio State Route 666, at Zanesville. Ohio State Route 60, at Zanesville. Ohio State Route 586, near Nashport.