Mouth- Just one cigarette causes "cigarette breath" and dulls the taste buds. The hot smoke is harmful to the mouth and throat tissues. Cigarette smoking plays a major role in causing cancer of the oral cavity and larynx.

Teeth- Tar stains the teeth, causing brown spots.

Bronchioles- As smoke is drawn into the respiratory tract, harmful gases and particles settle into the surrounding membranes (bronchioles). One point of great concentration is where the bronchus divides into left and right bronchi. This is also where most lung cancer begins.

Lungs- Efficiency decreases.

Fingers- Cigarettes cause yellow stains on fingers.

Cardiovascular system- Nicotine causes blood vessels to constrict, forcing the heart to pump faster and increase blood pressure. Smokers have a higher death rate from strokes. Smoking is also a risk factor in the development of cardiovascular disease, affecting the circulation in the arms, hands, feet, and legs.

Gastrointestinal tract- Cigarette smoking appears to be connected to increased illness and a higher death rate from peptic ulcers. Cigarette smoking reduces the effectiveness of standard ulcer treatment and slows the rate of ulcer healing.

Bladder- Smokers have a greater risk of bladder cancer than nonsmokers.