P. Manish Chandra                      Work                      Outing                      Another World                      Res    

PUBLICATIONS

Immobilization of alkaline protease from Conidiobolus macrosporus for reuse and improved thermal stability.
Aparna Tanksale, P. Manish Chandra, Mala Rao and Vasanti Deshpande (2001)
Biotechnology Letters., 23; 51-54.     Link

Cloning, preparation and preliminary crystallographic studies of penicillin V acylase autoproteolytic processing mutants.
P. Manish Chandra, James A. Brannigan, Asmita Prabhune, Archana Pundle, Johan P. Turkenburg, G. Guy Dodson and C. G. Suresh (2005) Acta Cryst., F61; 124-127.     Link

WORKING PAPERS

Auto-proteolytic processing of Penicillin V Acylase is simpler than of other related Ntn hydrolases P. Manish Chandra, James A. Brannigan, Guy Dodson and C. G. Suresh (Manuscript communicated)

Polymorphism shown by the crystals of Penicillin V Acyalse from Bacillus sphaericus P. Manish Chandra, Eleanor Dodson, Guy G. Dodson and C. G. Suresh (Manuscript being communicated)

Co-crystal structure of Penicillin V Acylase with substrate Penicillin V: Insight in to catalytic specificity P. Manish Chandra, Guy G. Dodson and C. G. Suresh (Manuscript ready)

Penicillin V Acylase mutant being envisaged as transformed enzyme: P. Manish Chandra, Guy G. Dodson and C. G. Suresh (Manuscript being prepared)

POSTER PRESENTATIONS

P. Manish Chandra, Jim Brannigan, Asmita Prabhune, Archana Pundle, Johan Turkenburg, Guy Dodson, C. G. Suresh
Structural studies of four inactive mutants of Penicillin V Acylase from Bacillus sphaericus.
Presented at the IVth meeting of Asian Crystallographic Association, IISc, Bangalore, India. Section A6: Crystallography in Biology, medicine and pharmacology, A6-12

P Manish Chandra, Jim Brannigan, Asmita Prabhune, Archana Pundle, Johan Turkenburg, Guy Dodson and C. G. Suresh
Studies on Auto-Proteolytic activation and Catalysis of Penicillin V Acylase from Bacillus sphaericus
Presented at the XXXIIIrd National Seminar on Crystallography, NCL, Pune, India. Abstract: P22

P. Manish Chandra, Jim Brannigan, Asmita Prabhune, Archana Pundle, Lorraine Hewitt, Johan Turkenburg, Guy Dodson and C. G. Suresh
Polymorphism shown by the crystals of Penicillin V Acylase from Bacillus sphaericus
Presented at the XXXIIIrd National Seminar on Crystallography, NCL, Pune, India. Abstract: P21