Valery R. Polyakov, Ph.D.

4 Lexington Ave.

Bound Brook, NJ 08805

valery.polyakov@aventis.com

 

Objective:

Be a member of a team of dedicated people where my affords have an impact on the success of the company.

 

Work Experience:

 

Oct. 2001 – Present

Aventis Inc. (Bridgewater, NJ) – Senior Scientist.

New technologies implementation and development. SOAP Web services. C#, ASP.NET. Molecular Modeling and ChemoInformatics tools: SciTegic Pipeline Pilot, Sybil, ISIS, Chemical databases. Evaluation of software from outside vendors, technical due diligence.

Support for Chemical Biology proteases platform. Proteases profiling, library design and enumeration, project support.

 

Jan. 2000 – Sept. 2001

ChemCodes Inc. (Durham, NC). Senior Chemistry Software Scientist (Lead Software Engineer). Developing software for Chemistry and Mass-Spectroscopy lab automation; High throughput support for Combinatorial Chemistry; Real time data collection and processing to MS SQL/Oracle databases; Web-based data analysis tools.

Single- and Multi-Threaded COM/COM+ development in Visual C++ and Visual Basic; C# and .NET platform; User interface development in Java, ASP, DHTML,  UML.

Software lifecycle (Rational Unified Process): Taking and completing projects from inception to transition in the following roles:

-          Lead software developer for the series of COM/COM+ applications.

-          Project Manager for mass-spec auto-tuning software package and the system of software data analysis tools.

 

1996 – 1999

Postdoctoral Research Associate at Washington University Medical School. Member of a diverse team of Chemists, Medical Doctors, and Biologists dedicated to modern ways of drug discovery and whole body imaging development. Organic, Medicinal, Peptide Chemistry, Crystallography. Developing crystal structure visualization and structural formula drawing tools in Java/VB.

 

Oct. 1994 – 1996

Max-Planck Society Postdoctoral Scholar at Max-Planck Institute für Kohlenforschung (Mülheim a.d. Ruhr, Germany). Inorganic and Organometallic Chemistry, Crystallographic Computing. Developing programs for 3D structure rotation in C, C++.

 

Jan. – Sept. 1994

Fulbright Scholar at University of Minnesota, Duluth, MN. Crystallographic Computing. Structure file translators between from UNIX to PC

 

1992 – 1993

Assistant Professor at Kiev University. Inorganic Chemistry and Crystallography, Teaching Basic and Pascal to undergraduate students.

 

1988 – 1992 Ph.D. Student

 

1985 – 1988

Research chemist. Synthetic Organic Chemistry. RIAP chemical company, Kiev, Ukraine.

 

Education:

1992 – Kiev University, Ph.D. in Chemistry. Physical Inorganic Chemistry (real time data collection from a custom-build apparatus and processing on PC; languages: Assembler for Intel, Basic, C, Fortran)

1985 – Kiev University, Department of Chemistry, full-time student: MSc in Organic Chemistry, “red diploma” (“A” level, with distinction)

 

Grants and Scholarships:

1997    Siemens Scholarship - tuition for the ACA Summer School in Crystallography.

1994 - 1996     Max-Planck-Society Scholarship.

1994    Fulbright Scholarship.

1993    Research grant from the International Science Foundation

 

Additional Education and Qualifications:

2000    Microsoft Course # 1596, Building MTS Components with C++ 6

2000    Microsoft Course # 1639, Introduction to Microsoft Solutions Framework

2000    Microsoft Course # 1304, Component development Using ATL 3.0

1997    University of Georgia. ACA Summer Course in Crystallography.

1997    Washington University Medical School. Examination in knowledge of safety aspects of handling radioactive materials.

 

Recent Papers (20 total published papers, 14 patents, 1 patent application):

1.      Joseph A. Ocheskey,  Valery R. Polyakov, Scott E. Harpstrite, Anna Oksman, Daniel E. Goldberg, David Piwnica-Worms, Vijay Sharma Synthesis, characterization and molecular structure of a gallium(III) complex of an amine-phenol ligand with activity against chloroquine-sensitive strains. J. Inorg. Biochem. 2003, 93, 265-270.

2.      Valery R. Polyakov and Marian Czerwinski, Hydrogen-Bonding in Ethanol Adducts to Bis(3-R-penta-2,4-dionato)Nickel(II) Species. Inorganic Chemistry, 2001, 40 (18), 4798 – 4802.

3.      Polyakov, Valery; Sharma, Vijay; Dahlheimer, Julie L.; Pica, Christina M.; Luker, Gary D.; Piwnica-Worms, D. Novel Tat-Peptide Chelates for Direct Transduction of Technetium-99m and Rhenium into Human Cells for Imaging and Radiotherapy. Bioconjugate Chemistry 2000, 11(6), 762 – 771.

4.      Polyakov, V. R.; Dahlheimer, J.; Piwnica-Worms, D. Membrane permeant peptide conjugates for imaging caspase-3 activity in vivo. Proc. Am. Assoc. Cancer Res. 1999, 40, 729.

5.      Polyakov, V. R.; Sharma, V.; Cranckshaw, C; Piwnica-Worms, D. Synthesis, molecular structure and properties of a neutral shiff base phenolic complex of magnesium. Inorg. Chem. 1998, 37(18), 4740 - 4742.

 

References: On request