Name____________________________

Karyotyping Activity from www.biology.arizona.edu

In this activity, you will use a computer model to look at chromosomes and prepare a karyotype. You will diagnose three patients for abnormalites and learn the correct notation for characterizing karyotypes.

http://www.biology.arizona.edu/human_bio/activities/karyotyping/karyotyping.html

Follow the instructions at the site. As you proceed through the lesson, answer the following questions.

Introduction:

1. What causes a dark band on the chromosome?

2. What is a centromere?

Patient Histories:

Complete the karyotype for the patients by matching the chromsome with its homologous pair.
Hint: Use the sizes and banding pattern of the chromosome to help you make the match. (Your choices are highlighted in blue)
You will not be able to proceed until you have correctly matched all the chromosomes.

Patient A

3. (A.1) What notation would you use to characterize Patient A's karyotype?

4. (A.2) What diagnosis would you give for Patient A

Patient B

5. (B.1) What notation would you use to characterize Patient B's karyotype?

6. (B.2) What diagnosis would you give for Patient B

Patient C

5. (C.1) What notation would you use to characterize Patient C's karyotype?

6. (C.2) What diagnosis would you give for Patient C

Yay! You've just completed the patient diagnosis and karyotype section.

Now follow the link to "Internet Research"

Your task is to search the internet for sites relating to human genetics. When you've found one you like, answer the following. Use search engines like yahoo or google. (www.google.com or www.yahoo.com)

7. List three words you could type into the search engine to find information about the topic.

8. List the title of the site and the url (address at the bar at the top)

9. What did you like about the site?

10. Summarize what information can be found at the site.