Prostaglandin H2 synthase-1
Structure of the Prostaglandin H2 synthase-1 homo-dimer:
EGF-like domain (blue), amphipathic membrane binding motif (red), catalytic globular domain (grey), heme groups (brown), and arachidonic acid in its binding site (yellow). (1)
3-D structures of PGHS-1 (Rasmol)
Arachidonic acid bound to COX channel
Iodosuprofen(inhibitor) bound to PGHS-1
This website was created by Rima Estephan for a graduate Enzymology class
Proff. : Dr. Manfred Filipp
Institute: Graduate School and University Center / CUNY
last updated on 6/01/01