Isaac Nichols
- Born: about 1736
- Military: Revolutionary War

Children:
1.) Brittan Nichols Sr. - *

Brittan Nichols Sr.
- Born: South Carolina
Dorothy (Carlile) Nichols
- Born: South Carolina
- Died: about 1840 in Texas (Hopkins)

Children:
1.) Joseph Nichols - *
2.) Brittan Nichols Jr.
- Born: 14 Mar 1838 in Florida
- Military: Civil War (Private)
- Married: Elizabeth (Cooper) Nichols
- Died: 30 December 1908
3.) Nancy (Nichols) Cooper
4.) Peamelia (Nichols) Young

Joseph Nichols
- Born: 1813 in South Carolina
- Military: Civil War (Corporal)
- Died: 17 Feb 1904
- Buried: Cooper Cemetery, Louisiana (Beauregard)
Wife 1: Mary (Cooper) Nichols
- Born: 03 Mar 1820 in Georgia
- Died: 24 Jan 1896
- Buried: Cooper Cemetery, Louisiana (Beauregard)

Children:
1.) Isaac Nichols - *
2.) Miranda (Nichols) Claussner
- Born: 1845 in Alabama
- Married: Charles Claussner
- Died: after 1880
3.) Nancy (Nichols) Guess
- Born: 23 Feb 1847 in Alabama
- Married: Mark Guess
4.) Moses Nichols
- Born: 1850 in Alabama
- Died: 1860
5.) James Nichols
- Born: 1852 in Alabama
- Married: Amanda (Hoosier) Nichols
- Died: 1917
6.) Jackson Nichols
- Born: 1853 in Alabama
- Married: about 1876 to Sarah Abigail (Eaves) Nichols
- Died: 1902
- Buried: Cannon Cemetery, Louisiana (Beauregard)
7.) Austin Nichols
- Born: 13 May 1855 in Alabama
- Married: 24 February 1875 to Mary Charity (Meadows) Nichols
- Married: Maggie (Self) Nichols
- Died: 07 May 1927
8.) Jane (Nichols) Slaydon - *
9.) Britton Nichols
- Born: 01 Oct 1861 in Louisiana
- Married: Nancy E. (Musslewhite) Nichols
- Died: 1942
- Buried: Cannon Cemetery, Louisiana (Beauregard)
10.) Elizabeth (Nichols) Eaves
- Born: 01 Oct 1861 in Louisiana
- Married: 31 September 1880 to William Lonzo Yancy Eaves
- Died: 31 March 1920
- Buried: Cannon Cemetery, Louisiana (Beauregard)
11.) Joseph W. Nichols (Dr.)
- Born: 26 Feb 1865 in Louisiana
- Married: Millie (Whiddon) Nichols
- Died: 10 October 1928
- Buried: Cooper Cemetery, Louisiana (Beauregard)
12.) Jessie Nichols
- Born: 1867 in Louisiana
- Died: 1880

Children:
1.) Daniel Nichols
- Born: 1898 in Louisiana
2.) Hardy Nichols
- Born: 1900 in Louisiana

Isaac Nichols
- Born: 25 Dec 1842 in Alabama
- Military: Civil War (Private)
- Married: 05 Oct 1865
- Died: 29 Dec 1932
- Buried: Cooper Cemetery, Louisiana (Beauregard)
Amanda E. (Holiday) Nichols
- Born: 08 Jun 1848 in Georgia
- Died: 01 Jan 1928
- Buried: Cooper Cemetery, Louisiana (Beauregard)

Children:
1.) Joseph Marion Nichols
- Born: 27 Jan 1867 in Louisiana
- Married: Cora (Carroll) Nichols
- Died: 1961
- Buried: Cooper Cemetery, Louisiana (Beauregard)
2.) Thomas Jefferson Nichols
- Born: 17 Mar 1872 in Louisiana
- Married: Addie (Summers) Nichols
- Died: 07 July 1932
- Buried: Cooper Cemetery, Louisiana (Beauregard)
3.) James Irving Nichols
- Born: 10 Jan 1875 in Louisiana
- Married: Flora (Carroll) Nichols
- Died: 11 May 1959
- Buried: Cooper Cemetery, Louisiana (Beauregard)
4.) Jessie Barton Nichols
- Born: 15 Nov 1876 in Louisiana
- Married: Maude E. (Sanders) Nichols
- Died: 02 September 1965
- Buried: Cooper Cemetery, Louisiana (Beauregard)
5.) William Ira Nichols
- Born: 06 Feb 1879 in Louisiana
- Married: Mary Jane (Young) Nichols
- Married: Nina (Keller) Nichols
- Died: 1941
- Buried: Cooper Cemetery, Louisiana (Beauregard)
6.) Columbus Augustus Nichols - *

Columbus Augustus Nichols Sr.
- Born: 09 May 1883 in Louisiana (Calcasieu)
- Married: 28 Feb 1905
- Died: 01 Sep 1972 in Merryville, Louisiana
- Buried: Cooper Cemetery, Louisiana (Beauregard)
Florence Ursula (Eaves) Nichols
- Born: 14 Dec 1887 in Louisiana (Calcasieu)
- Died: 27 Jul 1968 in Merryville, Louisiana
- Buried: Cooper Cemetery, Louisiana (Beauregard)

Children:
1.) Willie Mae (Nichols) Meadows - *
2.) Ruby Rae (Nichols) Thompson
- Born: 14 November 1912 in Louisiana
3.) Mable (Nichols) Stamps
- Born: 09 Dec 1914 in Louisiana
- Married: Tracey Stamps
4.) Lois (Nichols) Blackman
- Born: 18 March 1917
- Married: J. C. Blackman
5.) Columbus Augustus Nichols Jr.
- Born: 1923 in Louisiana
- Died: 1924
- Buried: Cooper Cemetery, Louisiana (Beauregard)
6.) Max Nichols
- Born: Louisiana
7.) Edwin Nichols
- Born: 18 Apr 1926 in Merryville, LA
- Married: 13 March 1928 in Louisiana to Dovie (Hickman) Nichols
8.) B. Jennings Nichols