The History of Parkinson's Disease
A Timeline of events:
Meynert postulates between involuntary choreiform movements and the basal ganglia, etc. Chlorpromazine was found to produce symptoms similar to Parkinson's Disease
James Parkinson's An Essay on the Shaking Palsy is Published
Levadopa is introduced in therapy for Parkinson's Disease
MPTP was discovered as a toxin that could induce parkinson-ism.
MAO- Inhibitors are introduced as treatment for PD
Oldenstein points out "maceration"
of the substantia nigra
Tretiakoff links substantia nigra lesions to PD
Montagu finds dopamine in mammalian brains
1817
1887
1983
1868-1883 1960
1975
1952
1919
1985
1918
1868
1899 1938
1959 1969
1950s
First clinical trials using medullary transplant into the striatum were performed.
Osler's textbook of medicine describes treatment for PD during the early 1900s Amantadine's usefulness is discovered by Schwab et al.
Dopa decarb-oxylase discovered
Synthetic anti-cholinergic drugs introduced
Carlsson finds the specific area of Dopamine Concen-tration
Jackson believes cause of Parkinson's was in the cerebellum
Charcot studies Parkinson's Disease, notices rigidity, akinesia, etc. Gowers and Buzzard credit Parkinson as well.
A Description of PD
LINKS
This website was created by Lauren White in December, 2001.
Neuroscience Organizations, Associations, Societies
Famous People bringing attention to Parkinson's Disease