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HEPATITIS VACCINE LINKED TO START OF RA

Hepatitis B Vaccine Linked to Autoimmune Rheumatoid Diseases

SAN DIEGO, Nov. 9 /PRNewswire/ -- Data from France released at the 62nd Annual Meeting of the American College of Rheumatology, held November 8-12, 1998, in San Diego, California links immunization against hepatitis B to the development of autoimmune rheumatoid diseases such as lupus and rheumatoid arthritis. The rise of autoimmunity following hepatitis B immunization in school children and adults has become a major public health concern. In October, the Ministry of Health in France suspended routine hepatitis B immunization of school children while continuing hepatitis B immunization at birth. The reason for this decision was reportedly the increased risk of autoimmune diseases that has been associated with the vaccine when it is given starting at school age or later.

The data from France links hepatitis B immunization to both the development of newly diagnosed cases of autoimmune rheumatoid diseases as well as the exacerbation of previously diagnosed cases that were in remission. This finding is supported by data from Canada published in September which linked immunization against hepatitis B to the development of autoimmune rheumatoid diseases in firefighters.

John B. Classen, M.D. an immunologist at Classen Immunotherapies published papers linking the immunization against hepatitis B and other diseases to the development of insulin dependent diabetes, an autoimmune disease. Dr. Classen's work found that immunization starting after 2 months of life was associated with an increased risk of autoimmunity compared to starting at birth. Data from a small study published by the US government appears to support his data and showed that when hepatitis B immunization was given starting after 2 months of life it was associated with an almost doubling of the risk of diabetes.

"The data from humans and animals is very clear, when you stimulate the immune system with vaccines you increase the risk of autoimmunity and exacerbate smoldering inflammatory conditions. Vaccine induced autoimmunity is a major public health problem because of the number of vaccine doses given and the large percentage of people with undiagnosed inflammatory conditions. We need to develop ways of giving vaccines without increasing the risk of autoimmune diseases" states Classen.

"The French decision to continue hepatitis B immunization at birth while discontinuing immunization starting at school age suggests the French Ministry of Health may believe that they can decrease vaccine induced autoimmunity by giving vaccines starting in the first month of life. They appear to be accepting our findings" adds Classen. Dr. Classen's research has been published in numerous journals and featured in national news reports.

For the latest information on the effects of vaccines on insulin dependent diabetes and other autoimmune diseases visit the Vaccine Safety Website (http://vaccines.net).

For more information contact:
J. Barthelow Classen, M.D., M.B.A.; President of Classen Immunotherapies, Inc.
6517 Montrose Avenue, Baltimore, MD 21212 U.S.A.
Tel: 410-377-4549, Fax: 410-377-8526, Classen@vaccines.
net http://vaccines.net


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