This information was last updated on 12/16/1999.
Bonnie's original of this information is available at http://www.BonnieGr.com
Make sure that the vitamins are naturally coated, and that no sugar, preservatives, artificial colors or flavors, chemical solvents, or specific things that you may be allergic to are on the label. "USP" on the label is preferred.
The following recommendations are for those 10 yrs to adult (children 6 to 10 should follow the dosages in brackets), who have normal, healthy liver, gallbladder, kidney and heart functions and are not pregnant or nursing, or have active peptic ulcers. Always consult your physician before taking any supplements to be sure. DISCLAIMER: This approach may not work for everyone.
In the morning:
I give B complex for a balance of the B vitamins, so that a deficiency in one doesn't occur.
Foods that contain tyramine should be avoided if increasing symptoms- they are chocolate (large quantities), aged cheese, soy sauce, red wine, raisins, canned fish, pickled herring, chicken livers, cured meats, and most alcoholic beverages. They interfere with MAO inhibitors, if you are taking this kind of antidepressant, with severe consequences to your health -hypertensive crisis. Tyramine is a monoamine which is eliminated by monoamine oxidase (MAO). If MAO is inhibited, then tyramine is not broken down, releasing stores of norepinephrine, which have been found to be increased in TS in several studies. Tyramine also is an inhibitor of pyridoxal kinase, which decreases the active form of vitamin B6 in the body.
Go to an allergist and get tested for food allergies. Eliminate these foods from your diet to see if this helps, or try an elimination diet without the allergy testing. (Of course, get tested for respiratory allergies also!). Recent studies have shown that food allergies or sensitivites causes hyperactivity in the majority of cases. The allergy connection is also implicated in TS.
Cut out aspartame (NutraSweet). The high phenylalanine blocks other "Large Neutral Amino Acids", such as valine, leucine, isoleucine, tryptophan, tyrosine, histidine, and methionine from entering the brain. Aspartic acid, which is in aspartame, is an excitatory amino acid, which can act as a false transmitter, substituting for glutamic acid (glutamate). MSG (monosodium glutamate) should be avoided, also because of its glutamate portion, which excites neurons. Avoid caramel color, vanillin and yellow #5 (tartrazine). These inhibibit B6 activity.
Avoid pseudephedrine (Sudafed) containing decongestants and antihistamines. Eliminate other dyes (especially azo dyes) that may cause adverse reactions - especially red dye # 40. Caffeine should be eliminated. It is a methylated xanthine stimulant of the catecholamines, which are already stimulated in TS.
Essential fatty acids can be found in DHA and trout, crappie, haddock, sea bass, salmon, cod, and/or cold water halibut (the fatty fish).
Don't ingest many foods high in sugar. The best diet approach may be a semi vegetarian diet, which provides a balance of carbohydrates and protein, recognizing that adolescents need more protein than adults.
For information about my hypothesis and why I have chosen these supplements for my program please see: Bonnie Grimaldi: Hypothesis.
Bonnie Grimaldi, BSMT (ASCP) Medical Technologist, Laboratory Mt. Carmel East Medical Center 6001 E. Broad St. Columbus, Ohio 43213 (614) 234-6700 Bachelor of Science in Medical Technology from the University of Akron in Akron, Ohio Dec 1977 Graduate courses in Biochemistry at the University of Akron towards a Master's degree in Biology Certified by the American Society for Clinical Pathologists MT(ASCP) # 115060 Aug. 1977.Bonnie can be reached by e-mail.
Discalimer: All of the above is the result of Bonnie's research. I take no responsibility for it's accuracy. Please, before beginning any program of this sort, consult with your physician.
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