Terms for the Week
Terms that arose from transcriptionists for the past week.  See Archive   for past terms.

Definitions were from
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ifosfamide
<chemical> 3-(2-chloroethyl)-2-(2-chloroethylamino)tetrahydro-2h-1,3,2-oxazaphosphorine 2-oxide. Positional isomer of cyclophosphamide which is active as an alkylating agent and an immunosuppressive agent.
Pharmacological action: antineoplastic agent, alkylating, immunosuppressive agents.
Chemical name: 2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide
(12 Dec 1998)
t
elangiectasia
<clinical sign> A permanent dilation of preexisting blood vessels (capillaries, arterioles, venules), creating small focal red lesions, usually in the skin or mucous membranes. Also called telangiectasis.
(16 Dec 1997)

basal cell
<pathology> General term for relatively undifferentiated cells in an epithelial sheet that give rise to more specialised cells act as stem cells).
In the stratified squamous epithelium of mammalian skin the basal cells of the epidermis (stratum basale) give rise by an unequal division to another basal cell and to cells that progress through the spinous, granular and horny layers, becoming progressively more keratinised, the outermost being shed as squames.
In olfactory mucosa the basal cells give rise to olfactory and sustentacular cells.
In the epithelium of epididymis their function is unclear, but they probably serve as stem cells.
(13 Nov 1997)
sternocleidomastoid
<anatomy, muscle> ORIGIN: Sternum, clavicle INSERTION: Mastoid process ACTION: Bends head to same side, rotates head, raises chin to opposite side, together bend head forward and elevate chin
(27 Sep 1997)

klatskin's tumor (tumour-British)

Adenocarcinoma of the common hepatic duct bifurcation. These tumours are generally small, sharply localised, and seldom metastasizing. G. Klatskin's original review of 13 cases was published in 1965. Once thought to be relatively uncommon, tumours of the bifurcation of the bile duct now appear to comprise more than one-half of all bile duct cancers.
(12 Dec 1998)    
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parvovirus
A genus of the family parvoviridae, subfamily parvovirinae, infecting a variety of vertebrates including humans. Parvoviruses are responsible for a number of important diseases but also can be non-pathogenic in certain hosts. The type species is mice minute virus.
(12 Dec 1998)

colony stimulating factor
<growth factor> A group of lymphokines that induce the maturation and proliferation of white blood cells from the primitive cell types present in bone marrow such as the leucocyte, macrophage and monocyte lines.
(18 Nov 1997)
orchiectomy
The surgical removal of the testicles.
(12 Dec 1998)
orchidectomy
<procedure, surgery> Surgical removal of the testis. A recognised form of treatment for prostate cancer
seminoma
<oncology, tumour> A cancerous neoplasm, or abnormal growth, of the testicle which is thought to arise from primordial germ line cells while the individual is still an embryo and the testicle has not yet been sexually differentiated from the generic gonad.
(09 Oct 1997)