1. Now that the drawing's cleaned up, you can start colouring. I highly recommend creating layers for each section of your art, so it's easier to manage and you can perform moves and commands on one section without effecting the other.
For example, you can perform a lot of commands on the face portion of a character's head, but the hair portion is untouched and uneffected because it's in another layer.
2. The Layers window should look like this:
To open it, go to: Window, > Show Layers. You can also automatically hide or show it with the F7 button. In the beginning, you'll see that the default layer for your art is always called Background. This layer has limits where some commands and moves cannot be performed.
3. We'll create a new layer for Tammy's skin colour. To create a new layer, press: Layer, > New, > Layer. This is a hassle to me now that I'm used to pressing Ctrl+Shift+"N" instead.
Name: Name the new layer so it's easily definable.
Mode: I use Multiply mode for all the colour layers of my CGs. This makes the colour transparent, so that the lines can be seen.
Now we have a Layer specifically assigned for the skin colour. If you feel like renaming it, just double-click on that layer to open the layer options. 4. Usually, I create a new layer and fill it one at a time, but since the current CG is quite simple, I could predict the neccesary layers.
To be more disk space-efficient, it's wise to 'share' the layers. 'White Layer' for example, covers everything white in the CG, such as eye white and the shirt Tammy's wearing. 'Face&Ponytail&Uniform Layer' covers the eyes, mouth, the little ball used to tie the ponytail and that portion of her clothing which I don't know what to call since I'm not good with fashion terms....
You can tell if it's safe to share the layers if they're far away from each other (eg. the hair portion is far away from the shoes) or they're the same colour(eg.the character wears a shirt with matching stockings or the robot's body is mostly painted blue).