Yang Lab publications

  1. Jang-Won Lee, X Cindy Tian and Xiangzhong Yang. Failure of male pronucleus formation is the major cause for the lack of fertilization and embryo development in pig ICSI oocytes. Biol Reprod (in press) 2003

  2. Jang-Won Lee, Shin-Chih Wu, X Cindy Tian, Michele Barber, Thomas Hoagland, John Riesen and Xianghong Yang. Production of Cloned Pigs by Whole Cell Intracytoplasmic Microinjection. Biol Reprod (accepted) 2003.

  3. BP Enright, BS Jeong, X Yang and XC Tian. Epigenetic Characteristics of in vitro Cultured Donor Cells for Nuclear Transfer: Levels of Histone Acetylation. Biol Reprod (accepted) 2003.

  4. AF Savage, J Maull, XC Tian, M Taneja, L Katz, M Darre and X Yang. Behavioral Observations of Adolescent Holstein Heifers Cloned from Adult Somatic Cells. Theriogenology (in press) 2003.

  5. Enright, B., Taneja, M., Schreiber, D., Riesen, J., Tian, X-C., Fortune, J.E. and Yang, X.  Reproductive Characteristics of Cloned Heifers Derived from Adult Somatic Cells.  Biol. Reprod. 66:291-296.  2002.
  6. Liu, J-L., Sung, L-Y., Barber, M. and Yang, X.  Hypertonic Medium Treatment for Localization of Nuclear Material in Bovine Metaphase II Oocytes.  Biol. Reprod. 66:1342-1349.  2002.
  7.  Dinnyes, A., Tian, X-C. and Yang, X. Cloning of Rabbits (Chapter 17).  In: Principles of Cloning. Eds. JB Cibelli, RP Lanza, KHS Campbell and MD West.  Academic Press, San Diego, CA. pp. 344-366, 2002.
  8. Tian, X-C.,Lonergan, P., Jeong, B.S., Evans, A.E.O. and Yang, X.  Association of MPF, MAPK and nuclear progression dynamics during activation of young and aged bovine oocytes.  Mol Reprod Dev 62:132-138 2002.
  9. Liu, L., Deng, M., Tian, X-C. and Yang, X. Chapter 19. Principles and Practice of oocyte activation in mammals. In: Introduction to Mammalian Reproduction. Ed. Daulat Talsiani. (in press) 2002.
  10. Govoni, K.E., Tian, X-C., Kazmer, G.W., Taneja, M., Enright, B., Rivard, A.L., Yang, X. and Zinn, S-A. Age-related changes of the somatotropic axis in cloned Holstein calves.   Biol Reprod 66:1293-1298 2002.
  11. Liu, J-L., Sung, L-Y., Tian, X-C. and Yang, X. Hypertonicity-Induced Projections Reflect Cell Polarity in Mouse MII Oocytes: Involvement of Microtubules, Microfilaments, and Chromosomes.  Biol Reprod 67:1853-1863 2002.
  12. Du, F., Sung, L-Y., Tian, X-C. and Yang, X. Differential Cytoplast Requirement for Embryonic and Somatic Cell Nuclear Transfer in Cattle. Mol Reprod Dev (accepted) 2002.
  13. Xue, F., Tian, X-C, Kubota, C, Du, F., Taneja, M., Dinnyes, A., Dai, Y., Lewin, H., Pereira, L-V. and Yang, X. Aberrant patterns of X-Chromosome inactivation in bovine clones. Nature Genetics 31:216-220, 2002 (with world-wide press release).
  14. Tian, X-C., Kubota, C. and Yang, X. Cloning of aged animals - a medical model for tissue and organ regeneration. Trends in Cardiovascular Medicine 11:313-317  2001.
  15. Yang, X. and Xu, J.  Developmental changes of telomerase in oocytes and embryos. Advances in Reproduction 6:63-68, 2001.
  16. Jeong, B.S. and Yang, X. Cysteine, glutathione, and percoll treatments improve porcine oocyte maturation and fertilization in vitro. Mol Repro Dev 59:330-335, 2001.
  17. Deng, M.Q. and Yang, X. Full Term Development of Rabbit Oocytes Fertilized by intracytoplasmic Sperm Injection. Mol. Reprod. Dev. 58:1-6, 2001.
  18. Xu J. and X. Yang. Telomerase activity in early bovine embryos derived from parthenogenetic activation and nuclear transfer. Biol. Reprod. 64:770- 774, 2001.
  19. Dinnyes A., L. Liu, Y. Dai, M. Barber, J. Xu, P. Zhou and X. Yang. Development of cloned embryos from adult rabbit fibroblast cells. Biol. Reprod. 64:257-263, 2001
  20. Yang X and X. Tian. Cloning adult animals - What is the genetic age of the clones? Cloning 2: 117-122, 2000.
  21. Tian X., J. Xu and X. Yang. Normal telomere lengths found in cloned cattle. Nature Genetics 26:272-273, 2000.
  22. Xu J and Yang X Telomerase activity in bovine embryos during early development. Biol. Reprod. 63:1124-1128, 2000.
  23. Suzuki H., J.-C. Ju and X. Yang. Surface ultrastructural alterations of bovine oocytes after parthenogenetic activation. Cloning 2:69-78, 2000.
  24. Enright B.P., P. Lonergan, A. Dinnyes, T. Fair, F.A. Ward, X. Yang and M.P. Boland. Culture of in vitro produced bovine zygotes in vitro vs in vivo: Implications for early embryo development and quality. Theriogenology 54:659-673, 2000.
  25. Lonergan, P., A. Dinnyes, T. Fair, X. Yang, M.P. Boland. Bovine oocyte morphology and embryo development following meiotic inhibition with butyrolactone-1. Mol. Reprod. Dev. 57:204-209, 2000.
  26. Suzuki H., Jeong B.S. and X. Yang. Dynamic changes of cumulus-oocyte cell communication during in vitro maturation of porcine oocytes. Biol. Reprod. 63:723-729, 2000.
  27. Tripp M.W., J.C. Ju, T. A. Hoagland, J.W. Riesen, X. Yang and S.A. Zinn. Transvaginal ultrasound-guided oocyte retrieval in yearling beef heifers. Theriogenology 53:1581-1590, 2000.
  28. Kubota C., H. Yamakuchi, J. Todorki, K. Mizoshita, N. Tabara, M. Barber and X. Yang. Six cloned calves produced from adult fibroblast cells after long-term culture. Proc. Natl. Acad. Sci (USA) 97:990-995, 2000 (cover paper, accompanied by a PNAS commentary on the paper by Mario Capecchi, PNAS 97:956-957, 2000).
  29. Taneja M., P.E.J. Bols, A. Van de Velde, J. Ju, D Schreiber, M.W. Tripp, H. Levine, Y. Echelard, J. Riesen and X. Yang. Developmental competence of juvenile calf oocytes in vitro and in vivo: Influence of donor animal variation and repeated gonadotropin stimulation. Biol. Reprod. 62:206-213, 2000.
  30. Dinnyes A., Y. Dai, S. Jiang and X. Yang. Development of solid-surface vitrified (SSV) bovine oocytes following parthenogenetic activation, in vitro fertilization and somatic cell nuclear transfer. Biol. Reprod. 63:513-518, 2000.
  31. Yang, X., X.C. Tian, Y. Dai and B. Wang. Transgenic Farm Animals: Applications in Agriculture and Biomedicine. Agricultural Biotechnology 5:269-292, 2000.
  32. Suzuki H., T. Azuma, H. Koyama and X. Yang. Development of cellular polarity of hamster embryos during compaction. Biol. Reprod. 61:521-526, 1999 (cover paper, on cover of Biology of Reproduction for 6 issues, Jan-June 2000).
  33. Suzuki H., L. Liu and X. Yang. Age dependent development and surface ultrastructural changes of activated bovine oocytes. Reprod. Fertil. Dev. 11:159-165, 1999.
  34. Van de Velde A., L. Liu, P.E.J. Bols, M.T. Ysebaert and X. Yang. Cell allocation and chromosomal complement of parthenogenetic and IVF bovine embryos. Mol. Reprod. Dev. 54:57-62, 1999.
  35. Dinnyes A., P. Lonergan, T. Fair, M.P. Boland and X. Yang. Timing of the first cleavage post-insemination affects the cryosurvival of in vitro produced bovine blastocysts. Mol. Reprod. Dev. 53:318-324, 1999.
  36. Ju, J.-C., J. E. Parks and X. Yang. Thermotelerance of IVM-derived bovine oocytes and embryos after short-term heat shock, Mol. Reprod. Dev. 53:336-340, 1999.
  37. Liu, L. and X. Yang. Interplay of maturation promoting factor and mitogen-activated protein kinase during metaphase to interphase transition of activated bovine oocytes. Biol. Reprod. 61:1-7, 1999.
  38. Suzuki H., J.-C. Ju, J.E. Parks and X. Yang. Surface ultrastructural characteristics of bovine oocytes following heat shock. J. Reprod. Dev. 44:345-351, 1998.
  39. Taneja M. and X. Yang. Feature Article: Promises and problems of in vitro production of embryos by TVOR-IVF scheme in cows and heifer. Em. Trans. Newsletter16:10-12, 1998.
  40. Liu, L., J.C. Ju and X. Yang. Differential inactivation of maturation-promoting factor and mitogen-activated protein kinase following parthenogenetic activation of bovine oocytes. Biol. Reprod. 59:537-545, 1998.
  41. Kubota,C., X. Yang, A. Dinnyes, J. Todoroki, H. Yamakuchi, K. Mizoshita, S. Inohae, N. Tabara. In vitro and in vivo survival of frozen-thawed bovine oocytes after IVF, nuclear transfer, and parthenogenetic activation. Mol. Repro. Dev. 51:281-286, 1998.
  42. Yang, X., C. Kubota, H. Suzuki, M. Taneja, P.E.J. Bols and G.A. Presicce. Control of oocyte maturation in cows - biological factors. Theriogenology 49:415-508, 1998.
  43. Tian, X.C. and X. Yang. Life on the bio-pharm: therapeutic proteins form transgenic organisms. Mol. Med. Today. 4:424-425, 1998.
  44. Liu, L., J-C. Ju, and X. Yang. Parthenogenetic development and protein patterns of newly matured bovine oocytes after chemical activation. Mol. Reprod. Dev. 49:298-307, 1998.
  45. Suzuki, H., G.A. Presicce and X. Yang. Differential surface ultrastructural characteristics and volumetric dynamics of bovine oocytes during maturation in vivo versus in vitro. J. Mamm. Ova Res. 15:49-62, 1998.
  46. Suzuki, H., T. Fujiwara and X. Yang. Surface ultrastructural characteristics of the hamster oocyte and its investments during in vivo maturation. J. Mamm. Ova. Res. 14:191-198, 1997.
  47. Wu B., G. Ignotz, W.B. Currie and X. Yang. Dynamics of maturation promoting factor (MPF) and its constituent proteins during in vitro maturation of bovine oocytes. Biol. Reprod. 56:253-259, 1997.
  48. Wu B., G. Ignotz, W.B. Currie and X. Yang. Analysis of c-mos proto-oncoprotein and its association with tubulins in bovine oocytes during maturation in vitro. Biol. Reprod. 56:260-267, 1997.
  49. Presicce G.A., S. Jiang, M. Simkin, L. Zhang, C. Looney, R.A. Godke and X. Yang. Age and hormonal dependence of acquisition of oocyte competence in pubertal calves. Biol. Reprod. 56:386-392, 1997.
  50. Concannon, P., P. Roberts, B. Ball, D. Schlafer and X. Yang, Betty Baldwin and B. Tennant. Estrus, fertility, early embryo development, and autologous embryo transfer in laboratory woodchucks (Marmota monax). Lab. of Anim. Sci. 47:63-74, 1997.
  51. Wu, B., G. Ignotz, W. B. Currie and X. Yang. Temporal distinctions in the synthesis and accumulation of proteins by oocytes and cumulus cells during maturation in vitro of bovine oocytes. Mol. Repro. Dev. 45:560-565, 1996.
  52. Yang, X. Cellular and molecular regulation of oocyte maturation, activation and fertilization in cattle. Arq. Fac. Vet. UFRGS Porto Alegre 25: 84-92, 1996.
  53. Liu Z., R.H. Foote and X. Yang. Development of early bovine embryos in co-culture with KSOM, taurine, superoxide dismutase and insulin. Theriogenology 44:741-750, 1995
  54. Du F., S. Jiang and X. Yang. Beneficial effect of oocyte activation prior to and during nuclear transfer in cattle using in vitro matured oocytes 24 h of age. Reprod. Nutr. Dev. 35: 703-712, 1995.
  55. Yang B.K., X. Yang and R.H. Foote. Early development of IVM/IVF bovine embryos cultured with or without somatic cells in a simple serum-free medium and different concentrations of CO2 and O2. J. Reprod. Dev. 40:1-9, 1994.
  56. Presicce, G.A. and X. Yang. Nuclear dynamics of parthenogenesis of young and aged bovine oocytes following combined ethanol and cycloheximide treatment. Mol. Reprod. Dev. 37:61-68, 1994.
  57. Presicce G.A. and X. Yang. Parthenogenetic development of bovine oocytes matured in vitro for 24 hours and activated by ethanol and cycloheximide. Mol. Reprod. Dev. 38:380-385, 1994.
  58. Yang X., G.A. Presicce, L. Moraghan and S. Jiang and R.H. Foote. Synergistic effect of ethanol and cycloheximide on activation of freshly matured bovine oocytes. Theriogenology 41:395-403, 1994.
  59. Suzuki H., X. Yang and R.H. Foote. Surface characteristics and size changes of immature, in vitro matured and fertilized bovine oocytes. Mol. Reprod. Dev. 38:421-430, 1994
  60. Zhang J.J., J. Liu, J.G. Tchabo, X. Yang and M. DeMattina. Zona-opening of hamster oocytes: A comparative study using macro and micro-manipulation methods. Human Reprod. 9:137-140, 1994.
  61. Koyama, H., H. Suzuki, X. Yang, S. Jiang and R.H. Foote. Analysis of polarity of bovine and rabbit embryos by scanning electron microscopy (SEM). Biol. Reprod. 50:163-170, 1994.
  62. Yang, X., S. Jiang, P. Farrell, R.H. Foote and A.B. McGrath. Nuclear transfer in cattle: Effect of nuclear donor cells, cytoplast age, co-culture and embryo transfer. Mol. Reprod. Dev. 35:29-36, 1993.
  63. Yang, X., S. Jiang and R.H. Foote. Bovine oocyte development following different oocyte maturation and sperm capacitation procedures. Mol. Reprod. Dev. 34:94-100. 1993.
  64. Ellington, J.E., B.A. Ball and X. Yang. Binding of stallion spermatozoa to the zona pellucida after co-culture with oviductal epithelial cells. J. Reprod. Fert. 98:203-208, 1993.
  65. Giles, J.R., X. Yang, W. Mark and R.H. Foote. Pluripotency of cultured rabbit inner cell mass cells following injection into blastocysts or morulae. Mol. Reprod. Dev. 36:130-138, 1993.
  66. Yang, B.K., X. Yang and R.H. Foote. Effect of growth factors on blastocyst development of in vitro matured and in vitro fertilized bovine oocytes. Theriogenology 40:521-530, 1993.
  67. Yang, X. Nuclear transfer in cattle and rabbits: A review. CAASS J. 2:96-116. 1992.
  68. Yang, X., S. Jiang, A. Kovacs and R.H. Foote. Nuclear totipotency of cultured rabbit morulae to support full term development following nuclear transfer. Biol. Reprod. 47:636-643. 1992.
  69. Yang X. and G. B. Anderson. Micromanipulation of mammalian embryos: principles, progress and future possibilities. Theriogenology 38:315-335. 1992.
  70. Heuwieser, W., X. Yang, S. Jiang and R.H. Foote. Fertilization of bovine oocytes after microsurgical injection of spermatozoa. Theriogenology 38:1-9. 1992.
  71. Heuwieser, W., X. Yang, S. Jiang and R.H. Foote. A comparison between in vitro fertilization and microinjection of immobilized spermatozoa from bulls producing spermatozoa with defects. Mol. Reprod. Dev. 33:489-491, 1992.
  72. Foote, R.H. and X. Yang. Cloning Bovine Embryos. Reprod. Dom. Anim. 27:13-21. 1992.
  73. Yang, X. Featured article: Embryo cloning by nuclear transfer in cattle and rabbits. Em. Trans. Newsletter 9 (4):10-22, 1991.
  74. Yang, X. and R.H. Foote. Survival of bisected morulae transferred to synchronous and asynchronous recipients. Mol. Reprod. Dev. 26:6-11, 1990.
  75. Yang, X., J. Chen, Y. Chen and R.H. Foote. Improved developmental potential of rabbit oocytes fertilized by sperm microinjection into the perivitelline space enlarged by hypertonic media. J. Exp. Zool. 255:114-119, 1990.
  76. Yang, X., Y. Chen, J. Chen and R.H. Foote. Potential of hypertonic medium treatment for embryo micromanipulation. I. Survival of rabbit embryos in vitro and in vivo following sucrose treatment. Mol. Reprod. Dev. 27:110-117, 1990.
  77. Yang, X., L. Zhang, A. Kovacs, C. Tobback and R.H. Foote. Potential of hypertonic medium treatment for embryo micromanipulation. II. Assessment of nuclear transplantation on blastomere isolation, subzona insertion and electrofusion with intact or functionally enucleated oocytes in rabbits. Mol. Reprod. Dev. 27:118-129, 1990.
  78. Chen, Y., J. Li, M.E. Simkin, X. Yang and R.H. Foote. Fertility of fresh and frozen rabbit semen inseminated at different times is indicative of male differences in capacitation time. Biol Reprod. 41:848-854, 1989.
  79. Chen, Y., X. Yang and R.H. Foote. Timed breeding in rabbit with fresh and frozen-thawed semen and evidence of acrosome alteration following freezing and thawing. Anim. Reprod. Sci. 18:35-41, 1989.
  80. Yang, X. and R.H. Foote. Production of chimeric rabbit from morulae by a simple procedure. Gamete Res. 21:345-351, 1988.
  81. Hansel, W., H. W. Alila, J.P. Dowd and X. Yang. Control of steroidogenesis in small and large bovine luteal cells. Aust. J. Biol. Sci. 40:331-347, 1987.
  82. Yang, X. and R.H. Foote. Production of identical twin rabbits by micromanipulation of embryos. Biol. Reprod. 37:1007-1014, 1987.