Father: Marquis Giovanni Francesco III of Manatova
Born: July 14, 1484
Married: Unknown
Died: March 29, 1519

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Mother: Princess Isabella of Este
Born: May 18, 1474
Died: February 13, 1539

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Children:
1. Duke Federico II of Manatova (b.3/29/1500)
2. Cardinal Ercole of Roman Catholic Church (b.1505)
3. Princess Eleonora of Montferrat-Manatova (b.1506)
4. Duke Ferrante I of Guastalla (b.1507)
5. Cardinal Piero of Roman Catholic Church (b.1510)
5. Count Sigismund I of Manatova (b.1512)

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