The famous German author Gotthold Ephraim Lessing lived in Breslau for a time.
A website with famous East Prussians, many of whom are actually Silesians [in German].
Of the listof 30 the link above locates, the following were Jewish:
Felix
Hausdorff
Alfred
Loewy
Alexander
Weinstein
Hermann
Kober
Leopold
Kronecker
Kaete
Ephraim Marcus
Johann
Peter Gustav Lejeune Dirichlet's wife was one of Felix Mendelssohn's
sisters and had Jewish ancestry.
Eduard
Ernst Kummer's wife had Jewish ancestry, and was, in fact, a cousin
of Dirichlet's wife.