Lionel Jefferies and his brother, Madison, though they were Canadian, joined the American Military. Lionel had the mutant ability to manipulate flesh, bone and other organic components. He used his powers as a medic but went insane during wartime. Madison, who wasn't affected by Lionel's powers, captured him and placed him in psychiatric care. He remained there until Heather Hudson discovered him and accidentally freed him. He repaid her by physically converting into a rather monstrous appearance. Alpha Flight finally caugh up to Heather and Madison was finally able to get Lionel to turn his powers against himself, apparently healing his psychiatric trauma.

Lionel went on to form the New Life Clinic, sponsored by unknown persons. There, he was able to help cure the original Box of the Bends as well as to give him legs. Scramble, however, was not cured of his insanity as was mistakenly believed and he had used dead tissue to give Roger his legs. His insanity was also somehow transferred into Roger. Alpha discovered too late that Lionel was still insane, for, by that time, Roger and Lionel had formed Omega. After Lionel lobotomized Roger, Madison (who had now taken over the Box armor) killed him. Scramble was a mutant with the ability to transform the shape and nature of flesh, bone and most organic materials.

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