| Year | Result | Award | Category | For |
| 1986 | WON | Tony | Outstanding Featured Actress in a Musical | Sweet Charity |
| 1990 | WON | Emmy | Outstanding Supporting Actress in a Comedy Series | Cheers |
| 1991 | WON | Emmy | Outstanding Supporting Actress in a Comedy Series | Cheers |
| 199? | WON | LA Drama Critics Circle | Distinguished Achievement in Theater | Chicago (Regional) |
| 1995 | Nominated | Emmy | Outstanding Guest Actress in a Comedy Series | Frasier |
| 1997 | WON | Tony | Best Actress in a Musical | Chicago |
| WON | Astaire Award | Best Female Dancer | Chicago |
| WON | Drama Desk | Outstanding Actress in a Musical | Chicago |
| WON | Drama Legue | Distinguished Performance | Chicago |
| WON | Outer Critics Circle | Best Actress in a Musical | Chicago |
| 1998 | Nominated | Annie | Outstanding Individual Achievement for Voice Acting by a Female Performer in an Animated Television Production | All Dogs Go To Heaven: The Series |
| 1999 | Nominated | Emmy | Outstanding Supporting Actress in a Miniseries or Movie | Dash and Lilly |
| Nominated | American Comedy | Funniest Female Guest Appearance in a TV Series | Frasier |
| 2000 | Nominated | American Comedy | Funniest Female Guest Appearance in a TV Series | Frasier |
| 2002 | WON | Seattle Film Critics | Best Supporting Actress | Tadpole |
| 2003 | Nominated | Chlotrudis | Best Supporting Actress | Tadpole |
| Nominated | Golden Satellite | Best Performance by an Actress in a Supporting Role, Comedy/Musical | Tadpole |