Cancer immunotherapy .net
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Interleukin-2 (IL-2)
Mechanism of IL-2 therapy of cancer

Cancers sensitve to IL-2
Surgery and IL-2
Radiotherapy and IL-2
Chemotherapy and IL-2
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Our research group by specialism and by research center
Frequently Asked Questions (FAQs)
Why test local IL-2 therapy ...
It may work for all tumours! The data we have generated so far, strongly suggest that local IL-2 may be effective in many types of malignancies, with no non-responding tumour types so far.

Effective in end-stage disease! Our data indicate that local IL-2, unlike many other therapies, is very effective in stage III-IV tumours, resulting in 50-70% objective responsives, which are often cures. Since many other treatments are not so effective in end-stage cancer, local IL-2 is a vital option.

No side-effects! Well that's not entirely true, local IL-2 may cause a local painfull and red swelling at the site of injection. But in treatment for end-stage cancer this is considered a very mild, almost neglectible, side effect.

Local IL-2 is cheap! The general patent of IL-2 is expired. Currently, 20 million IU IL-2 cost about 250 euro (275 US dollar). In some studies we use 1 to 20 million IU IL-2, but we have also reported succesfull local IL-2 therapy in human patients with stage III-IV cancer using 0.45 million IU IL-2 (about 6 euro) per patient.
So many tumours, so little time ...
Although only a limited number of types of cancers have been studied, almost all malignant tumours that were tested responded to local IL-2 therapy. We are always interested in testing the efficiency of local IL-2 therapy in other types of cancer.

Ideally, we would like to test local IL-2 for every
human and veterinary tumour that exists. Of course this is impossible to do for us. The veterinarian data actually works in two ways, it is a suitable veterinarian therapy and it is additional data with clinical relevance for human therapy. That is why we seek cooperation with skilled vets and medical doctors specialised in all sorts of cancer.
What we can offer ...
We have an international network of cooperating medical, veterinairy and biomedical researchers. We are experienced in the planning, performing, analyzing and reporting clinical studies.
What we need from you,
a skilled clinical doctor:
- clinical selection of patients

- a skilled clinical diagnosis in patients

- treatment of patients with conventional therapy

- treatment of patients with local IL-2 therapy

- follow-up of patients for tumour progression, disease-free survival and overall survival

- data collection.

We can help you with:
if desired, we can help you with:

- preclinical research for specific tumour types

- preclinical research for combined treatment of local IL-2

- experimental design of local IL-2 therapy, including combined treatment and selection criteria and ethical issues

- histopathological confirmation of tumours

- statistical analysis of your research

- writing scientific papers for internation peer-reviewed journals

of course, if you want you can do one, more or all of these things yourself

If you are a doctor and want to cooperate,

please contact us at!

Information for doctors
Information for patients
Information on the research group
Frequently asked questions
I want to
support this research