For night-fighting purposes some Me 210 were delivered to II./NJG 1 and were later on 1943 replaced by Me 410s.
| Unit | Radio Code |
| NJG 101 | 9W+ |
| I./NJG 1 | G9+ |
| II./NJG 1 | G9+ |
| 5/1. Légi század "Bagoly" |
In Hungary th Me 210 in the Ca-1 version was builded by the Dunai Repülögépgyár (Danube Aircraft Factory) under the Mutual Armament Program between Germany and Hungary. Two-thirds of this aircraf factory were to be delivered to Luftwaffe and the rest to the Honvéd Air Force. Even if it was mainly used as a Gyorsbombázó (fast bomber), the Me 210 Ca-1 was also used by the 5/1. night fighter Squadron known also as Bagoly (Owl) Squadron sited at Ferihegy airfiled in 1944.
The main operational nigh fighter version of the Hornisse was the Me 410 A-2/U2, fitted with nose radar aerials, a 50 mm BK 5 nose cannon for bomber destroyer purposes, two MG 17 machine guns and two 20 MG 151 cannons in an all-front armament configuration, except for the rear MG 131 barbettes. This was one of the most wonderful gun configurations of the Hornisse because of its tremendous destruction power. The BK 5 was a troublesome cannon for its automatic reloading system jammed easily; even though, a single round could bring down a four engine bomber hit in any part from a 1000 yds.
Some units non specialised in night interception duties used Me 410 Zerstörers for special night missions. Among these units was V./KG 2 which had its first casualty in Me 410 on the night of 13-14 July 1943; it was Feldwebel Zwissler’s and Oberfelbwebel Raida’s U5+KG, shot down by a Mosquito NF XII of No 85 Squadron. Also V./KG 2 (U5+) and 14./KG 2 used Me 410 Bs (U5+) in night attack operations. Oblt. Abrahamczik’s Me 410 had painted in black its undersurfaces for this purpose; he was the squadron leader of 14./KG 2.
Some Me 410s were used together with Ju 188s during the battle of Normandy for high-altitude night reconnaissance missions.
Like a small flash in the darkness of the active career of the Hornisse, Hauptmann Puttkammer, during a long-range night-fighting action of the II./KG 51, shot down five English heavy bombers over British territory flying his radar equipped Me 410. Also I./NJG 5 and III./NJG 1 employed Me 410 A1’s and B2’s, but with scarce success. They had no radar equipment. Some rare Hornisse’s with GM-1 system were flown as Mosquito chasers, also with little success. The career of the Me 410 as night fighter ended with the entry of the much expected He 219 A-6, Ju 88 G-7 and Ta 154’s.
| II./KG 51 | I./NJG 5 |
| III./NJG 1 | 14./KG 2 |