Photo
courtesy CNN (Tom Pidgeon/Allsport)
| Opponent | Result |
| Notre Dame | Win 26-22 |
| Rice | Win 37-3 |
| Syracuse | Win 18-13 |
| Wisconsin | Win 21-16 |
| Purdue | Win 38-12 |
| Michigan State | Lose 31-34 |
| Illinois | Lose 29-35 |
| Indiana | Win 34-31 |
| Northwestern | Win 37-3 |
| Penn State | Win 31-27 |
| Ohio State | Win 24-17 |
| Alabama
(Orange Bowl0 |
Win 35-34 |
Final Record 10-2
Photo
courtesy CNN (Tom Pidgeon/Allsport)
Tom Brady passed for 2586 yards and 20 touchdowns in his senior year. He finished his career passing for an Orange Bowl record 369 yards and 4 touchdowns leading Michigan to a 35-34 victory over Alabama in Miami.
Final Statistics For The 1999 Season
| Michigan | Opponent | |
| Points | 361 | 247 |
| Points Per Game | 30 | 21 |
| First Downs | 256 | 196 |
| Rushing Attempts | 462 | 439 |
| Rushing Yards | 1462 | 1450 |
| Rush Yds Per Game | 122 | 121 |
| Passing Yards | 3177 | 2546 |
| Pass Yds Per Game | 265 | 212 |
| Pass Alt/Comp/Int/TDs | 437/264/8/23 | 356/184/10/18 |
| Completion Percentage | 60.4% | 51.7% |
| Total Offense | 4639 | 3996 |
| Total Offense Per Game | 387 | 333 |