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  Using a virus as a genetic vehicle has an advantage over simply injecting the growth factor. buy real legal steroids new pro stack Bad side effects of steroids.  The effects of a single viral treatment last significantly longer (months if not years) because the muscle cell itself is constantly overproducing its own IGF-1 from injected DNA. The fact that the IGF-1 produced by the muscle of these mice did not reach the blood stream is interesting.  Systemic injections of IGF-1 have not been successful in inducing this kind of anabolic effect in humans. buy real legal steroids new pro stack Muscle boys.  In addition, IGF-1 produced by the liver is genetically different than that produced by muscle tissue.  It could be that providing additional DNA for the muscle to produce it's own IGF-1 is the key to achieving anabolic and rejuvenative effects specifically in skeletal muscle. In this study there was a preferential preservation of type IIb muscle fibers in aging mice. buy real legal steroids new pro stack Steroid ratings.  These are the fibers most sensitive to muscle hypertrophy from training and they are also the first fibers to disappear with aging.  In the mice receiving the engineered virus, there was also a preservation of the motor neuron, leading to an increase in functional capacity.  It is speculated that age related muscle loss is secondary to the loss of neuronal activation of type-II fibers.  By preventing the degeneration of typ-II motor units, functional capacity could be maintained into old age.  This technique may also serve useful in the prevention of osteoporosis.  Further study is necessary to determine wether IGF-1 is having an effect only on muscle fibers or on nervous tissues as well. Finally, it was also exciting to see muscle growth in the young mice who received the injection (15% increase in muscle mass).  This means that the injection provided levels of IGF-1 far and above what the muscle normally has access to and not simply a preservation of normal levels.  Remember that this was not combined with exercise.  The growth of the injected muscles happened even without an extreme mechanical stimulus.  The mice were simply allowed to run around as they usually do.  Because of these dramatic results, the authors expressed concern about the use of this technique to enhance performance or cosmetic appearance.  
  
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