| Day | Date | Opponent | Location | TV | Time |
| Saturday | Oct. 23 | Blue-White Scrimmage | Cameron Indoor Stadium | 6:15 | |
| Tuesday | Nov. 2 | Five-Star Hawks | Cameron Indoor Stadium | W, 128-80 | |
| Monday | Nov. 8 | Down Under All-Stars | Cameron Indoor Stadium | W, 123-63 | |
| NABC Coaches vs. Cancer Classic | |||||
| Thursday | Nov. 11 | Stanford | New York, NY | espn2 | L, 80-79 (OT) |
| Friday | Nov. 12 | Connecticut | New York, NY | espn2 | L, 71-66 |
| Saturday | Nov. 20 | Army | Cameron Indoor Stadium | HTS | W, 100-42 |
| Tuesday | Nov. 23 | Columbia | Cameron Indoor Stadium | W, 99-82 | |
| Saturday | Nov. 27 | ^USC | Anaheim, CA | W, 81-68 | |
| Tuesday | Nov. 30 | #Illinois | Chicago, IL | ESPN | W, 72-69 |
| Saturday | Dec. 4 | DePaul | Cameron Indoor Stadium | ESPN | W, 84-83(OT) |
| Saturday | Dec. 11 | at Michigan | Ann Arbor, MI | CBS | W,104-97 |
| Sunday | Dec. 19 | North Carolina A&T | Cameron Indoor Stadium | W, 101-60 | |
| Tuesday | Dec. 21 | Davidson | Cameron Indoor Stadium | RJ | W, 109-65 |
| Sunday | Jan. 2 | William & Mary | Cameron Indoor Stadium | HTS/FSS | W, 96-55 |
| Wednesday | Jan. 5 | at Virginia | Charlottesville, VA | ESPN | W, 109-100 (OT) |
| Sunday | Jan. 9 | at Maryland | College Park, MD | CBS | W, 80-70 |
| Wednesday | Jan. 12 | Georgia Tech | Cameron Indoor Stadium | ESPN | W, 82-57 |
| Sunday | Jan. 16 | at Florida State | Tallahassee, FL | RJ | W, 85-54 |
| Wednesday | Jan. 19 | N.C. State | Cameron Indoor Stadium | ESPN | W, 92-88 (OT) |
| Saturday | Jan. 22 | at Wake Forest | Winston-Salem, NC | CBS | W, 75-61 |
| Saturday | Jan. 29 | Clemson | Cameron Indoor Stadium | RJ | W, 93-59 |
| Thursday | Feb. 3 | at North Carolina | Chapel Hill, NC | RJ/espn2 | W, 90-86 (OT) |
| Saturday | Feb. 5 | Virginia | Cameron Indoor Stadium | ABC | W, 106-86 |
| Wednesday | Feb. 9 | Maryland | Cameron Indoor Stadium | RJ | L, 98-87 |
| Saturday | Feb. 12 | at Georgia Tech | Atlanta, GA | RJ/espn2 | W, 84-65 |
| Wednesday | Feb. 16 | Florida State | Cameron Indoor Stadium | ESPN | W, 101-68 |
| Saturday | Feb. 19 | at N.C. State | Raleigh, NC | ABC | W, 71-66 |
| Tuesday | Feb. 22 | Wake Forest | Cameron Indoor Stadium | RJ | W, 96-78 |
| Saturday | Feb. 26 | St. John's | Cameron Indoor Stadium | CBS | L, 83-82 |
| Wednesday | Mar. 1 | at Clemson | Clemson, SC | ESPN | W, 92-78 |
| Saturday | Mar. 4 | North Carolina | Cameron Indoor Stadium | ABC | W, 90-76 |
| Thurs. | Mar. 9 | ACC Tournament (vs. Clemson) |
Charlotte, NC | ESPN/RJ | W, 94-63 |
| Saturday | March 11 | ACC Championship (vs. Maryland) | Charlotte, NC | ESPN/RJ | W, 81-68 ACC Champs |
| Friday | Mar. 17 | NCAA First Round (vs. Lamar) |
Winston-Salem | CBS | W, 82-55 |
| Sunday | Mar. 19 | NCAA Second Round (vs. Kansas) |
Winston-Salem | CBS | W, 69-64 |
| Friday | Mar. 24 | NCAA Regional Semifinal Round (vs. Florida) |
Syracuse, NY | CBS | L, 87-78 |