The
War Years - Something goes terribly wrong!
In this chapter you are now an Army General responsible for deploying troops world-wide during WWII.
Let us say it is 1940 and we believe
we "might" have a cure for Yellow Fever. We have tried a few failed
attempts at developing a vaccination.
Maybe one of these we could call HBV? The world explodes in war. Pearl
Harbor is bombed Dec 7, 1941. We, the Americans, enter the war against
Nazi Germany in Europe, and fight against the Japanese in the Pacific.
Troops will be sent world-wide. Yellow Fever is considered a subtropical
disease and is found in the South Pacific. U.S. Forces will have to island-hop
across the wide South Pacific Ocean in order to recapture islands recently
occupied by advancing Japanese forces. A sudden priority is placed on protecting
the troops from Yellow Fever. It also exists in Africa and that is the
1st place U.S. Troops go to fight in the war.
It is decided that the Allied Powers,
(the U.S. and England, etc. .) would first defeat the Axis powers (Nazi
Germany, Japan, etc..), in Europe and
then, and only then, would all resources be directed towards the Pacific
Campaign, and the eventually surrender of the Japanese people. So you,
as the persons responsible, authorize to quickly develop a vaccine and
to immunize the troops scheduled for overseas deployment. In order to be
somewhat safe, you conduct a test. Since all "common sense" has left the
planet for at least 4 years, you drop the prior moral and ethical caveats
(limits) that had prevented full trials with humans in the past.
You trust others to develop the vaccine
quickly and safely. The "trusted soles" decide to take a natural form,
or version, of a similar virus, lets
call this "OLD"HBV, and you mix it with Yellow Fever. They both effect
the
liver, so you think they are related
at this time. You need to obtain serum to "stabilize" the vaccine prior
to
injection. You look to where, on a
huge global map in your office, your troops will be sent. You see the South
Pacific Ocean stretching halfway across
your wall. You want to make sure the military is protected against
Yellow Fever, because of its disastrous
effects on a standing Army. You circle the area that will represent the
middle of where they will fight. You look to an area that is halfway between
Japan and the Samoan Islands. That area is Northern Australia.
There are a group of people there that
live in the Northern Australian Outback that are culturally compared to
the American Indians. They are called
the Aborigines, and are considered to be the native population of
Australia. They are very friendly and
welcome outsiders openly. You have scientists and medical persons
collect some serum from these people.
You do this because their population has been in the area for
thousands of years. Hence, maybe they
have built-up an immunity to certain subtropical diseases. You
authorize this "serum" to be made into
a "stabilizer" for Yellow Fever. You can not know what you are doing
yet. DNA discovery is still 14 years
away! You create a concoction, or swill, of DNA and RNA that reacts with
the "Aboriginal serum". You test your
inoculation by formulating a hypothesis, and then collecting data to
support or disprove your hypothesis.
70,000 men will be tested you decide and, eventually authorize. One third
will get the virus, one third will not, and the last third will be soldiers
that already have had "Hepatitis". This mixture forms a sort of a hybrid-type
creature.
Both the Hepatitis B virus and the Yellow Fever Virus are somehow attached to each other either by, insertion or, attached to terminal nodes or ends. In some manner these two coexist on cellular level for years. The "New" virus helps your cause. It initially, does not kill anyone. With Yellow Fever you are dead in weeks or months.
"The Troops are protected", it is publicly proclaimed. It is 1942.
A year later things do not look so encouraging.
Something is terribly wrong and you do not have the level of
knowledge yet to understand what that
is. Years later it is learned that 51% of the Aboriginal population that
donated serum had been exposed to the
Hepatitis B virus. 56 years later Australia has a big problem with
Hepatitis C. You, the General, decide
to treat the recently infected troops with a new type of serum! It takes
another year to develop and the process
in the factory that makes the "stabilizer" out of serum has been
contaminated with the Hepatitis B virus
antigens and DNA . The manufacturer will call this "new" serum ISG.
It is 1944.
Before you give it to all, this time
you will test a smaller population. You test 2,000 troops. Results of the
tests
will not be known for 30-40 years yet.
Finally, the world war II is over. We win the war! Yeah! All the heroes
go
back to their communities in 48 states
to become the "bucs" of their neighborhoods. They are the first to give
blood because they are men and, more importantly, they are the heroes!
Blood banking and immunology is not what it should be, midway through the
American Century. Especially, if you are going to tinker with
genetics.
This "new" virus works itself into the
general population's blood supply. All knowledgeable persons call it
"Post-Transfusion associated Hepatitis",
also it is known as "Serum" Hepatitis at this time. Serum because
it was derived from the serum of humans.
Later it will be called "viral" hepatitis, as opposed to "bacterial"
hepatitis. These will later be called
Hep A (HAV) bacterial, Hep B (HBV), viral, and the "new" virus that is
neither "A" nor "B" is called "Non-A Non-B" or written just "NANB". Better
yet, let us just call this new "creature" Hepatitis C (HCV). All three
viruses are completely different from one another. Except, they are similar
in the organ that they attack, the liver. All three attack liver cells
called hepatocytes. (hepta = pertaining to the liver).
You retire as a famous General with
many medals and in all splendid glory. You are held up to all as an
example to follow. You feel you have
done your job well and have protected millions of persons world-wide.
In 1985 it will be established that
up to 330,000 persons were infected with this new virus that was created
to
prevent Yellow Fever. The virus starts
to travel through the blood supply and the blood banks. The new virus emerges
publicly in 1989, when a test is developed to screen and to find it.
Today, globally, persons afflicted with
HCV have skyrocketed to somewhere near 100-200 million persons
world-wide!