- Accession Number
- TY457-0010
- Document Delivery
- TY457: Document Delivery available
- Authors
- Karadag
E. Saraydin
D. Cetinkaya
S. Guven
O.
- Title
- IN VITRO SWELLING STUDIES AND PRELIMINARY BIOCOMPATIBILITY EVALUATION OF
ACRYLAMIDE-BASED HYDROGELS
- Source
- Biomaterials. 17(1):67-70, 1996 Jan.
- ISSN
- 0142-9612
- Author Keywords
- Hydrogels. Acrylamide-based hydrogels. Swelling. Human serum.
Biocompatibility.
- Abstract
- In this in vitro study, the biocompatibility of acrylamide-based hydrogels
such as acrylamide/crotonic and acrylamide/itaconic acid, prepared by using
gamma-rays, has been investigated against some biochemical parameters of
human serum. The swelling kinetics of acrylamide/crotonic and acrylamide/itaconic
acid hydrogels are investigated in distilled water and physiological saline
solution-and some swelling and diffusion parameters have been calculated.
For the analysis of biocompatibility, acrylamide/crotonic and acrylamide/itaconic
acid hydrogels are incubated in 10 different human sera for 24 h and their
biocompatibilities with some biochemical parameters have been investigated.
No significant difference in values before and after the test procedures
have been found. It is therefore concluded that acrylamide/crotonic and
acrylamide/itaconic acid hydrogels are biocompatible. [References: 14]
- Language
- English
- Publication Type
- Article
- Subset
- Current Contents/Life Sciences.
- CC Categories
- Experimental biology & medicine.
- Institution
- Reprint available from:
-
Karadag E
-
CUMHURIYET UNIV
DEPT CHEM
SIVAS 58140
TURKEY
-
CUMHURIYET UNIV
FAC MED
SIVAS 58140
TURKEY
- HACETTEPE UNIV
DEPT CHEM
ANKARA 06532
TURKEY