The Seven have been relieved of their duties and replaced by a federal marshal named Bryce. The seven go their seperate ways. With the absence of the seven, Guy Royal and Staurt James work together with Earl to take over the town of Four Corners. When the marshal is gunned down by Earl and his men, the seven reunite to rid the town of the lowly vermine.

Vin is arrested by a federal marshal named Yates and sent back to Texas. But the marshal is really in league with Eli Joe, the man who Vin suspects killed the man Vin is accused of killing. Eli Joe tries to hang Vin, but he is stopped by Chris. All of Eli Joe's gang is rounded up except for Eli Joe. Vin and the gang decide to go after him. But Eli Joe is already in town waiting to kill Vin in an ambush. Vin an Eli Joe struggle in a fight and Chris has to shot Eli Joe to save Vin's life.

Inez is being hunted by Don Pablo for spurning him, humiliating him and then stealing one of his horse's to get away. Don Pable wants to take her back, but Buck steps in and is challenged to a duel. The duel turns out to be with swords, so Inez decides to run and save Buck from the fight. But Vin convinces her that running is not the answer and she stays. In a great sword fight Buck is being ripped to pieces by Palbo. But Buck will not give up and in the end he overcomes Palbo and tells him to leave. Palbo can not accept this defeat and goes after Buck who is forced to kill him.

Chris's father-in-law, Hank, comes to town looking for help. Hank is running from the Nichol's family, a well known crime family from Kansas City.  Ma Nichols is the leader of the family and she is seeking revenge against Hank for killing her oldest son. Hank suspected her son of killing his daughter and grandson.

Dicky O'Shea is a greedy landowner who tries to steal land from a bunch of homesteaders traveling to the new land. Judge Travis decides the land belongs to the homesteaders and suspecting trouble, has the seven ride with the wagon train for protection.  Dicky is unsatisfied with this and seeks destruction of the group. He brings in a Powder man to scare off the settlers and when that doesn't work, to blow up the settlers. The seven defeat Dicky and the homesteaders are free to settle the land.  It turns out that there is a posibility of gold on the land.  

Obadiah Jackson is a black man accused of killing a white man in a local town.  The sherriff and the citizens of the town want to hang Obadiah without a trial.  The Judge wires the seven to come immediately to help move the trial to Four Corners, where the accused will have a better chance at a fair trial.  It turns out that Obadiah is Nathan's father.  The man Obadiah killed was their owner, back when they were slaves, and he was responsible for the death of Nathan's mother.  The verdict was Guilty and the sentence hanging.  But the sentence was to be carried out at the Judges convenience, which is not accepted by the sherriff.  A fist fight ensues and the seven, plus Obadiah, send the sherriff and his men back to their town.