Dr.Joe's Data Base
#: 668228 S12/Pregnancy & Sex [DIABETES]
25-Nov-96 00:17:04
Sb: Impotence Treatment
Fm: Paula D.-SYSOP 73021,567
To: all
Last week, the FDA gave Vivus, Inc. clearance to sell its MUSE
(alprostadil) urethral suppository for the treatment of erectile dysfunction.
MUSE provides a dose of a type of a synthetic prostaglandin called
alprostadil. It does not require any injections or pumps, and consists of a
very small suppository that is inserted about 1 inch into the urethra with a
disposable plastic applicator.
A study of 996 men with organic erectile dysfunction in a 3 month
home-treatment study found that about 65% of the men using MUSE had
intercourse at least once, compared to 19% of the men using a placebo.
Among the men for whom MUSE was successful, using MUSE resulted in sexual
intercourse about 7 times out of ten. The most common side effect reported,
mild and transient penile pain, occurred in about 11% of use.
The company expects to begin shipping the product in early 1997.
For more information on MUSE, search the forum Library here and call the
MUSE Information Center at 1-888-367-MUSE (888-367-6873).
#: 669083 S12/Pregnancy & Sex [DIABETES]
26-Nov-96 20:48:30
Sb: #668228-Impotence Treatment
Fm: Larry Lands 70353,2773
To: Paula D.-SYSOP 73021,567
Paula,
Thanks for the post about MUSE. I have been hearing about this product
for a long time, and have been waiting for a concrete announcement.
I was one of the first people to try papaverine injections several years
ago, but while they worked wonderfully, they were extremely painful for me.
I'm very hopeful this new process works as well, without the painful
injection.
Larry L
#: 669355 S12/Pregnancy & Sex [DIABETES]
27-Nov-96 06:06:01
Sb: #669083-Impotence Treatment
Fm: Paula D.-SYSOP 73021,567
To: Larry Lands 70353,2773
Dear Larry,
It's great to see the continuining advancements in treatment options!
I hope when it hits the pharmacies it will be in the easily-affordable range
so that many will be able to give it a try.
- Paula
#: 669345 S12/Pregnancy & Sex [DIABETES]
27-Nov-96 04:22:12
Sb: #668228-Impotence Treatment
Fm: Cathie Segal-SYSOP 104125,505
To: Paula D.-SYSOP 73021,567
Thank you for getting this info for us Paula.
I will be calling the number in the morning.
Cat
#: 669356 S12/Pregnancy & Sex [DIABETES]
27-Nov-96 06:07:44
Sb: #669345-Impotence Treatment
Fm: Paula D.-SYSOP 73021,567
To: Cathie Segal-SYSOP 104125,505 (X)
Dear Cat,
That sounds terrific -- I hope they have lots of good information!
- Paula
#: 670275 S12/Pregnancy & Sex [DIABETES]
29-Nov-96 09:59:29
Sb: #669356-Impotence Treatment
Fm: Cathie Segal-SYSOP 104125,505
To: Paula D.-SYSOP 73021,567
I called the MUSE Info line and there is a packet of info that should be on
the way here now. The gentleman who answered told me that I was one of the
first callers who was not a medical professional but that he expected many
more calls because there had been a newscast
about MUSE the night before in San Antonio.
The info he gave me over the phone was.......it should be in the Pharmacies
by the second or third week in January......that
The info he gave me over the phone was that it should be shipping by the
second week in January....that it would only be available through
Urologists......that they would not recommend it's use more than twice a day
(I must admit I did giggle at this one..wanting to comment about making up
for lost time but I didn't), that erections last anywhere from 30 to 90
minutes and that it would come with the recomm recommendation that it be used
in the doctors office the first time.
As soon as the info packet gets here I will post more info.
Cat
#: 670369 S12/Pregnancy & Sex [DIABETES]
29-Nov-96 18:01:31
Sb: #670275-Impotence Treatment
Fm: Larry Lands 70353,2773
To: Cathie Segal-SYSOP 104125,505
Cat,
>> I called the MUSE Info line...<<
Yeah, I placed the same call as you, and got the same responses. My only
significant unanswered question now is about the cost. Just how much is an
old run up the flagpole going to cost, anyway?
BTW, I find it extremely humorous that the two people discussing it here
(you & Paula) are *female*! Hmmmm...
Somewhere around mid January I'll let you know the *male* perspective on
how it works. I plan to be standing in line when it shows up.
Larry L ;-> [in Honolulu]
#: 670485 S12/Pregnancy & Sex [DIABETES]
29-Nov-96 21:50:32
Sb: #670369-Impotence Treatment
Fm: Dave Groves Wizop 76703,4223
To: Larry Lands 70353,2773
I will be watching closely, Larry!
#: 670761 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 16:03:28
Sb: #670369-Impotence Treatment
Fm: Cathie Segal-SYSOP 104125,505
To: Larry Lands 70353,2773
>>...find it extremely humorous.....<<
<s> One way or another we have to get the word out Larry :) It isn't exactly
the easiest thing to discuss in public....but it is important and Linda
taught me a few years ago that if I really wanted to be able to help SO's
here on the forum I needed to be able to discuss impotency.
The approval of MUSE by the FDA sounds like it will be a wonderful step
forward for diabetic guys and their SO's too. <blush>
Because of the long term effects of injectibles....Neil's Urologist refuses
to recommend them. Hopefully there are no side effects that will have to be
worried about with MUSE either.
Cat
#: 670739 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 14:41:21
Sb: #670275-#Impotence Treatment
Fm: Paula D.-SYSOP 73021,567
To: Cathie Segal-SYSOP 104125,505 (X)
Dear Cathie,
It's interesting that it will only be available through urologists.
Perhaps that's a wise idea. It also seems wise to do the first application
in the office, to get the knack of applying it without unnecessary pain --
here's hoping that will be done with a free sample! (g) It sounds terrific
that they will be able to start distributing it in January --what a promising
way to start the year!
Looking forward to hearing more,
Paula
There is 1 Reply.
#: 670762 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 16:03:29
Sb: #670739-#Impotence Treatment
Fm: Cathie Segal-SYSOP 104125,505
To: Paula D.-SYSOP 73021,567 (X)
I wonder what that means exactly? Can *who* prescribes something be
controlled by the pharmacies I wonder? If they only ship it to Urologists,
does that mean it won't be covered with Prescrption coverage?
Dr. Ron? Dr. Alan? Are you reading this? <S>
Cat
There are 3 Replies.
#: 670778 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 17:46:50
Sb: #670762-#Impotence Treatment
Fm: J.Garcia,DDS-SYSOP 104125,502
To: Cathie Segal-SYSOP 104125,505
Cat it will be expensive, I figure around 20 dollars a shot <G> But in some
cases insurance will pay up to 80% of that . If you want I can give you a
contact in a P message who can explain this to you. Caverject is available in
any pharmacy with a RX from an MD .
This will probably be the case with MUSE
Joe
There is 1 Reply.
#: 670858 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 19:52:17
Sb: #670778-#Impotence Treatment
Fm: Dave Groves Wizop 76703,4223
To: J.Garcia,DDS-SYSOP 104125,502 (X)
Heck caverject is $25.
There is 1 Reply.
#: 670874 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 20:11:48
Sb: #670858-Impotence Treatment
Fm: J.Garcia,DDS-SYSOP 104125,502
To: Dave Groves Wizop 76703,4223
Thats the Bama Tax !!!!!
Jose
#: 670947 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 23:29:27
Sb: #670874-#Impotence Treatment
Fm: Dave Groves Wizop 76703,4223
To: J.Garcia,DDS-SYSOP 104125,502 (X)
All sorts of "sin" tax here. <g>
There is 1 Reply.
#: 670969 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 23:53:03
Sb: #670947-Impotence Treatment
Fm: J.Garcia,DDS-SYSOP 104125,502
To: Dave Groves Wizop 76703,4223
Yup thats the southern way !!!!!
#: 671188 S12/Pregnancy & Sex [DIABETES]
01-Dec-96 12:07:48
Sb: #670778-#Impotence Treatment
Fm: Cathie Segal-SYSOP 104125,505
To: J.Garcia,DDS-SYSOP 104125,502 (X)
>>Caverject is available in any pharmacy with an RX from an MD<<
Neil's Urologist will not prescribe injectibles so Caverject or any of other
injectibles made up by a Urologist are not, for all intents and purposes
available to us. Yes, he could change Urologists, but he likes the one he
has and trusts his judgment that the long term effects are not worth it.
From the information I had found and posted here a year or so ago...and from
what I was told on the phone on the MUSE Info line..... MUSE is a small pill
that is inserted in to the end of the penis with an applicator of some sort
which begins to dissolve when a small amount of urine passes through the
penis.
As soon as we get the information package from them, I'll get the info posted
here.
Cat
There are 2 Replies.
#: 671199 S12/Pregnancy & Sex [DIABETES]
01-Dec-96 13:22:27
Sb: #671188-Impotence Treatment
Fm: J.Garcia,DDS-SYSOP 104125,502
To: Cathie Segal-SYSOP 104125,505 (X)
That is right Cat some uros won't use injectables. And please keep us
informed. Thanks
Joe
#: 671211 S12/Pregnancy & Sex [DIABETES]
01-Dec-96 13:45:19
Sb: #671188-Impotence Treatment
Fm: Dave Groves Wizop 76703,4223
To: Cathie Segal-SYSOP 104125,505 (X)
They showed the MUSE applicator on Network News last night. The "pill" is
tiny and the applicator tiny. According to CBS (I think) it is going to be a
huge money maker as the baby boomers join the 11mm diagnosed impotents
already in the market. I expect they feel $25/use is cheap. I can't imagine
most folks using it more than 1x per day, but that would be AT LEAST a $30mm
a month or $3.6 BILLION a year industry of it's own to start.
#: 671776 S12/Pregnancy & Sex [DIABETES]
02-Dec-96 22:02:23
Sb: #671211-#Impotence Treatment
Fm: Cathie Segal-SYSOP 104125,505
To: Dave Groves Wizop 76703,4223 (X)
$25 PER USE?????
At that price 90% of the people who need it won't be able to afford it.
<sigh>
There is 1 Reply.
#: 671869 S12/Pregnancy & Sex [DIABETES]
03-Dec-96 00:25:35
Sb: #671776-Impotence Treatment
Fm: Dave Groves Wizop 76703,4223
To: Cathie Segal-SYSOP 104125,505 (X)
Yup, they took lessons from some call-girls I know. <sigh>
#: 672666 S12/Pregnancy & Sex [DIABETES]
04-Dec-96 23:24:49
Sb: #671869-Impotence Treatment
Fm: Larry Lands 70353,2773
To: Dave Groves Wizop 76703,4223
>> they took lessons from some call-girls I know. <sigh> <<
**ROFL!!**
Larry L [in Honolulu]
#: 672759 S12/Pregnancy & Sex [DIABETES]
05-Dec-96 00:50:14
Sb: #672666-Impotence Treatment
Fm: Dave Groves Wizop 76703,4223
To: Larry Lands 70353,2773
<g> Larry, My roomate was in the business for quite a while. She almost
appreciates my complications. <g>
#: 670804 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 18:10:20
Sb: #670762-Impotence Treatment
Fm: J.Garcia,DDS-SYSOP 104125,502
To: Cathie Segal-SYSOP 104125,505
Sorry about the formatting but I can't modify it. This a very nice file on
the feelings of Women. RE impotence.
Joe
"Other Side" of ImpotenceWhat Women Think: New Survey Explores "Other
Side"
of Impotence -Sixty-five Percent of Women are Unaware of Treatment
OptionsAccording to a national survey conducted under the auspices of
theImpotence Institute of America (IIA), a majority of adult American
womenare happy with their sex lives and expect to be sexually active,
onaverage, to age 75. Yet many of these women may find their
sexualexpectations unmet, in part because of male impotence which affects
abouthalf of all men by age 70.While impotence can thwart sexual expectations
of the woman, the surveyfound 80 percent of women surveyed whose partner has
experienced impotencehad not encouraged their partner to seek help. They
didn't believe thattheir partner could be helped by treatment. In fact, 65
percent of thewomen surveyed were unaware of any available treatment options
forimpotence.The IIA survey, released in connection with Impotence Awareness
Month(September), was sponsored by an educational grant from The Upjohn
Company.The phone survey explored the sexual behavior, knowledge and
attitudes ofadult women (18-50+) toward male impotence and its potential
effect ontheir sexual relationships.Sexual Longevity and ImpotenceEighty
percent of the women surveyed consider sex to be an important partof their
lives, while 83 percent indicated they are satisfied with theircurrent sexual
relationship. In addition, the survey found that as a womanages she expects
herself to be sexually active longer. Middle age (35-49)and older women (50+)
expect that they will be sexually active until theyare about 80 years old,
while younger women (18-34) see themselves sexuallyactive only to age 70.As
women grow older, however, their expectations for continued sexualactivity in
their 60s, 70s and 80s may not be fully realized because of therising
incidence of impotence among aging males.According to J. Francois Eid, M.D.,
director of the Erectile DysfunctionUnit at The New York Hospital-Cornell
Medical Center, the age when a manmay begin to experience erection difficulty
is unpredictable, but theincidence increases rapidly for men in their
mid-50s. By age 70, it isexpected that at least half of the male population
will experience someerectile difficulties."Women should understand the
relationship between aging and impotence sothat they are prepared, should
their partner ever experience erectiledifficulties," said Dr. Eid. "The most
important thing for a couple toremember is that impotence is treatable at any
age."According to Eid, between 10 and 20 million men in the U.S. suffer
fromsome degree of erectile dysfunction, commonly known as impotence.
However,only one in 20 men with erectile problems seeks medical attention.
Eidbelieves the lack of action may be caused by embarrassment and/or lack
ofknowledge about the condition and treatment options.Responding To
ImpotenceFor those women whose partners have experienced impotence, most
reportedthat they felt "frustration" (41 percent) and to a lesser
extent"disappointment" (29 percent) and "rejection" (18 percent). A
significantnumber of women (40 percent) reported that they felt some
responsibilityfor their partner's problem, which, according to Eid, is not
uncommon."Until recently, many medical experts believed impotence was caused
bymental or emotional conflicts," said Eid. "Today, experts believe that upto
80 percent of all cases may be due to physical conditions, withpsychological
factors accounting for the remaining 20 percent."Impotence can result from
complications of chronic conditions such ascoronary artery disease, high
cholesterol levels, high blood pressure anddiabetes mellitus. Side effects of
surgery, medication and psychologicalinfluences are also associated with
impotence, as are lifestyle factorssuch as a high-fat diet, drug abuse,
excessive alcohol consumption andsmoking.Coping with an Impotent
Partner"Women play an integral role in the successful treatment of impotence
andthis survey justifies the need for greater impotence education
andawareness among women," said Eid. The study revealed that partners of
olderwomen (50+) were more likely (14 percent) than the partners of younger
ormiddle-aged women to have ever experienced impotence. Of those women
whosepartner has never experienced impotence, nearly half (45 percent)
believethat it would cause at least some problems in their relationship.Among
women whose partner has never experienced impotence, most said theywould
address the problem directly, rather than ignore it. Actions citedmost
frequently by respondents for dealing with impotence include talkingwith
their partner (56 percent), seeking professional counselling (47percent), or
thinking of creative new ways to explore intimacy (42percent).Marion Parker,
president of the IIA, which operates the support groupImpotents Anonymous and
I-ANON for partners, says that more than half ofall calls received on the IIA
toll-free hotline come from women. "Women arebeginning to assume a larger
role in the treatment of impotence," saidParker adding, "their growing
involvement makes successful treatment morelikely for their
partners."According to the survey, only a small number (4 percent) of women
wouldconsider extreme measures in dealing with their partner's impotence,
whichincludes terminating the relationship or initiating sexual
relationsoutside of the relationship. Most women surveyed (72 percent) agree
thatimpotence is a "couple's problem.""Because impotence is a concern
shared
by both men and their partners, it'simportant that they seek medical advice
and treatment as a couple," saysEid. "Couples who work together are much more
likely to find a mutuallysatisfying treatment for impotence."Impotence
Treatment OptionsAccording to Eid, men and their partners now have effective
treatmentchoices that weren't available in the past. The newest form of
therapy forerectile dysfunction is a small-needle injection into the side of
the peniswith Caverject Sterile Powder (alprostadil for injection), which
isreconstituted with sterile water prior to administration. This is the
firstand only approved medication currently available for the treatment
oferectile dysfunction. Caverject has an effectiveness rate of more than
80percent. The most common side effect of the medication is mild to
moderatepain that occurs in about a third of men and is usually well
tolerated.Other recommended treatment options noted by Eid include lifestyle
changes,vacuum devices and penile implants. Regardless of the option
selected, manyexperts see counseling as helpful to many in the treatment
process."The IIA can provide men and their partners with information on
supportgroups, treatment options and medical specialists in their area."
saidParker. "We pride ourselves on helping men and their partners deal with
theimpotence treatment process."Founded in 1983 by Bruce and Eileen
MacKenzie, the IIA is a non-profit,non-vested health association dedicated to
supporting men affected byimpotence, the physicians and clinics who treat
them and manufacturerswhose products help impotent men. Affiliated with the
IIA are ImpotentsAnonymous and I-ANON, a national network of over 50 support
groups forsuffers and their partners.The Institute also provides a toll-free
"Help-Line", available to anyoneseeking information about impotence.
Consumers can call 1-(800) 669-1603 toreceive additional literature on
impotence and information on local supportgroups
meetings.--------------------------------------------------------------------
------
#: 671235 S12/Pregnancy & Sex [DIABETES]
01-Dec-96 14:33:26
Sb: #670804-#Impotence Treatment
Fm: Cathie Segal-SYSOP 104125,505
To: J.Garcia,DDS-SYSOP 104125,502 (X)
Great article Joe. And some of the very things that are mentioned in it are
why I do try to post or follow up on messages about new impotency treatments.
I also am not hesitant to mention impotency in conferences when people ask
about complications. As you know it is not something that is easily
discussed by many people, men and women alike. Just saying that it is a
common problem can lift a lot of weight from people's shoulders even if they
can't bring themselves to talk about it online.
I try and find a happy medium in messages.....get the word out, but not be so
graphic that people will call CSI and complain.
Thanks for the article.
Cat
There is 1 Reply.
#: 671241 S12/Pregnancy & Sex [DIABETES]
01-Dec-96 15:01:13
Sb: #671235-Impotence Treatment
Fm: J.Garcia,DDS-SYSOP 104125,502
To: Cathie Segal-SYSOP 104125,505
Glad you liked it Cat !!!
Joe
#: 670857 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 19:52:15
Sb: #670762-Impotence Treatment
Fm: Dave Groves Wizop 76703,4223
To: Cathie Segal-SYSOP 104125,505
Any practicing MD can prescribe.
#: 671190 S12/Pregnancy & Sex [DIABETES]
01-Dec-96 12:10:08
Sb: #670857-#Impotence Treatment
Fm: Cathie Segal-SYSOP 104125,505
To: Dave Groves Wizop 76703,4223 (X)
>>Any practicing MD can prescribe<<
I found it rather odd that the folks at the MUSE info line said it would ONLY
we available through Urologists too, but I'm just "reporting" what they said
<G>.
There is 1 Reply.
#: 671212 S12/Pregnancy & Sex [DIABETES]
01-Dec-96 13:45:21
Sb: #671190-Impotence Treatment
Fm: Dave Groves Wizop 76703,4223
To: Cathie Segal-SYSOP 104125,505 (X)
Hey, since when are pharmaceutical houses right? Look at Lilly who says
Humalog is counterindicated for kids and pumpers?
#: 670776 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 17:40:00
Sb: #668228-Impotence Treatment
Fm: J.Garcia,DDS-SYSOP 104125,502
To: Paula D.-SYSOP 73021,567 (X)
Hi Paula, I am glad to see that this topic is being addressed outside of the
confines of the "private sections".
At this point alprostadil is available and BTW is very effective in an
injectable form. The commercial name is Caverject and has been approved by
the FDA since last year. It is a kit with a vial of powder and a liquid
diluent. These have to be mixed and injected into the Cavernous tissue of the
male organ. The syringe comes with the kit. This injection dilates this
tissue and permits blood to flow in producing an erection which can last up
to 2 hours. Since impotence is a very common complication of DM this
substance has been a godsend to millions of DM's and non DM's who have
erectile dysfunction and their mates as well. Impotence is a problem that
affects not only the impotent but his mate as well.
There are other injectables that will produce the same results, papaverine
and prostaglandine. Which are not FDA approved but are Rx'ed by many
urologists because they are just as effective as Caverject and much cheaper.
A Caverject kit (comes in 2 dosages (10 and 20) costs about 20 dollars, a
vial of papaverine good for about 10 injections costs about 40 dollars. And
may be injected with a 30 gauge insulin syringe which BTW is much better than
the syringe that comes with the kit.
This is not a "cure" for impotence it is a "treatment" much like
insulin is
for DM. And a major drawback is that after a few years of injections you may
have complications like scarring and fibrosis. Alhough in MHO the rewards of
renewing an active and very good sex life are worth the risk. And you can
always opt for the second stage scenario which is a penile implant.
MUSE is an acronym for Medicated Urethral System for Erection and if the hype
is true, it will truly be a blessing for the 10 million or so impotent men in
the US and millions in the rest of the world. The promise is that it will
work just as well as the injectables without the discomfort of an injection
and reducing the risk of fibrosis significantly.
This is the news flash on MUSE ...
<
Aug. 09, 1995
A new treatment for impotence has been successful in more than 70
percent
of men tested -- and does not require shots, surgery or pumps.
Instead, it uses a device called the Medicated Urethral System for
Erection (MUSE) -- a small plunger, about one-eighth-inch diameter at
the
tip, that
is briefly inserted into the urethral opening, where it releases a
pellet
of erection-inducing medication that is absorbed into the mucous
membranes.
Typically men with erectile dysfunction self-inject the penis with
muscle-relaxing drugs, which dilate the blood vessels. That method,
however, sometimes results in a prolonged and painful erection,
impotency experts say.
"The new system is a real breakthrough," said Dr. Culley Carson III, a
urologist at the University of North Carolina School of Medicine in
Chapel Hill. "It's going to improve the ability of men to use medication
to
restore their erections in a way that we haven't been able to accomplish
before."
In most cases, erectile dysfunction is thought to be caused by physical
problems like diabetes, excess alcohol consumption, smoking, multiple
sclerosis or the side effects from prescription drugs.
In a study of 234 men who had not achieved an erection for an average of
four years, 76 percent of the men achieved an erection after the MUSE
treatment. Less than 3 percent of men who were treated with a placebo
experienced the same effect.
Researchers say injecting erection-producing drugs is generally more
effective, but that the MUSE treatment will probably prove more
attractive
to many men.
"Given the choice, most people would use a little pellet at the end of
the urethra rather than injecting medicine," said Robert Krane of the
University of Southern California School of Medicine.
The device, manufactured by Vivus Inc. in Menlo Park, Calif., is
expected
to be on the market by 1997.
Compiled from staff and wire reports.
------------------------------------------------------------------------
-- Copyright 1995 San Diego Union-Tribune>>
As of this moment there are 2 other important products in development.
One is A gel with the drug which you just apply and have the same results.
And the other is Sildenafil. which is an oral drug.
>>>Sildenafil
ORLANDO, Fla.--An oral medication for impotence, still in the
early stages of testing, significantly improved erections and
sexual performance in the majority of men who took the drug,
according to a British study presented here.
Though preliminary, the research is important because there are
currently no effective oral agents to treat the condition, said a
New York researcher.
The drug, sildenafil, produces more natural erections by
enhancing the erectile activity that occurs with sexual
stimulation, said lead researcher Clive J.C. Gingell, M.D., a
consultant urologist at the Bristol Urological Institute in
Bristol, England.
Specifically, sildenafil inhibits phosphodiesterase-5, an enzyme
involved in smooth-muscle relaxation.
Unlike other treatments for erectile dysfunction, the drug does
not directly cause erections, but instead enhances erectile
activity associated with sexual stimulation and excitation, Dr.
Gingell said.
The study involved 351 men with sexual dysfunction of no known
cause. The men were either given a placebo or one of three daily
doses of sildenafil: 10 mg, 25 mg or 50 mg for 28 days.
After the treatment period, 38% of placebo patients reported
improvement in their erections--while 89% of the men taking the
highest dose of sildenafil reported improved erectile activity
and sexual performance.
"The results appear to be good in men with psychogenic erectile
dysfunction," said Arnold Melman, M.D., chairman of urology at
Albert Einstein/Montefiore Medical Center in New York. "Whether
the drug works in men who have organic erectile dysfunction is
another matter entirely."
If an effective oral treatment for erectile dysfunction were
available, every man would want to try it, Dr. Melman noted, as
only injectable drugs are on the market. --C.B.>>>>
The principle in all these "treatments" is the same, a system to deliver a
drug to the Corpora Cavernosum tissue in the male organ to produce an
erection. The difference lies in the how to go about it. Injectables are very
effective but a non invasive system with the same results is preffered. Thus
MUSE, Gel and Sildenafil.
Muse is a semi non invasive system in which a small pellet is placed in the
urethra with an applicator, this pellet dissolves and permeates through the
skin to produce the same resullts as the injectables. It is certainly
preferable to a needle !!!!
If I had some money I would invest heavily in any of these companies.
Impotence has been a scourge to men, and women I might add, since ALWAYS !!!!
Entire herds of rhinos, tigers and bears have been wiped out because men
thought and still think, erroneously that their horns, or other organs are
aphrodisiacs.
Men are very touchy about this issue and I am very glad to see that the women
members and sysops on this forum have been the ones to bring it out. I
applaud you !!!!!!
In section 22 the "male room" we have been discussing these topics for ages.
And even though it is a "private" section and anonymity is guaranteed
participation is very small. Although we have many "success" stories and I
have a passel of private messages attesting to the help received .
I would be glad to privately or publically help any member, male or female
who needs information. I have tons of material some of which is in the
librariesand can be accessed by doing a library search with the keyword
Impotence.
At this moment there is no need to for man or woman, except in unusual
circumstances where the plumbing doesn't work to suffer the deprivation that
impotence brings.
Sex is the great leveler in life, available to all. We should not be deprived
of it.!!!!!
Joe
#: 670921 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 22:49:12
Sb: #670776-Impotence Treatment
Fm: RobinHarrison-SYSOP 73670,3675
To: J.Garcia,DDS-SYSOP 104125,502
How informative, Joe. Thank you! This has been an excellent thread, and I
too am glad to see impotence and potential help for it being discussed
publicly. I think this thread will be a great library upload! :)
Robin
#: 670942 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 23:17:53
Sb: #670921-Impotence Treatment
Fm: J.Garcia,DDS-SYSOP 104125,502
To: RobinHarrison-SYSOP 73670,3675
Well I am astonished !!! that make 2 things we have agreed on !!!
Joe
#: 670963 S12/Pregnancy & Sex [DIABETES]
30-Nov-96 23:47:47
Sb: #670921-Impotence Treatment
Fm: J.Garcia,DDS-SYSOP 104125,502
To: RobinHarrison-SYSOP 73670,3675
Just kidding Robin !!! BTW since somebody said I am running things >g> you
are elected to keep this thread going and eventually to bundle it into a very
valuable addition to our library. I am very glad to see this issue in a
"public" area (hey who cares anyway?). This is a most important topic for
diabetics (there I go again !!!) for PWD . And bringing it to your section
gives it much more exposure than in 22 or 23 . I would like to congratulate
Paula especially for bringing it up and all the women who have responded!!!
Kudos for Cat also !!! Despite the <blush>
This is one of my pet topics for obvious reasons and I was getting a little
frustrated dealing with this most serious complication of DM in the confines
of the "male room" . We have been taught that sexuality is not to be
discussed in "mixed" company but hey this is almost the second millenium. And
a good and "decent" sex life is something to treasure.
Joe
#: 671039 S12/Pregnancy & Sex [DIABETES]
01-Dec-96 01:51:36
Sb: #670963-Impotence Treatment
Fm: BrookeDisbrow-SYSOP 74627,3163
To: J.Garcia,DDS-SYSOP 104125,502
>> I was getting a little frustrated dealing with this most serious
complication of DM in the confines of the "male room" .<<
That's the reason some of us didn't want the (P) sections in the first
place.
#: 671121 S12/Pregnancy & Sex [DIABETES]
01-Dec-96 03:51:06
Sb: #671039-Impotence Treatment
Fm: Dave Groves Wizop 76703,4223
To: BrookeDisbrow-SYSOP 74627,3163
Me first and foremost, but then none of ya'll had to listen to the flaming
phone calls from members who were incensed by the open discussions that were
going on at the time.
#: 671203 S12/Pregnancy & Sex [DIABETES]
01-Dec-96 13:38:01
Sb: #671121-Impotence Treatment
Fm: BrookeDisbrow-SYSOP 74627,3163
To: Dave Groves Wizop 76703,4223 (X)
Thank goodness! <g>
#: 673023 S12/Pregnancy & Sex [DIABETES]
05-Dec-96 16:00:15
Sb: #MUSE
Fm: J.Garcia,DDS-SYSOP 104125,502
To: All
This notice of approval for MUSE was taken directly from the FDA homepage
Joe
<Original Application #: 020700
Approval Date: 19-NOV-96
Trade Name: MUSE
Chemical Type: 3
Therapeutic Potential: P
Dosage Form: SUPPOSITORY
Applicant: VIVUS INC
Active Ingredient(s): ALPROSTADIL
OTC/RX Status: RX
Indication(s): Treatment of erectile dysfunction
There is 1 Reply.
#: 673025 S12/Pregnancy & Sex [DIABETES]
05-Dec-96 16:18:22
Sb: #673023-MUSE
Fm: J.Garcia,DDS-SYSOP 104125,502
To: J.Garcia,DDS-SYSOP 104125,502 (X)
This a news flash before it was approved
<New Treatment for Impotence
Air date: November 9, 1995
Studies have shown that up to 30 million men in this country suffer from
impotence. That's 52 percent of all men between the ages of 40 and 70,
suffering
some degree of not being able to get an erection. Earlier this week, we told
you
about the stick-on testosterone patch, which can help improve the sex lives
of men
with low hormone levels. Now, a Menlo Park company, Vivus, has developed a
radical new way for men to deliver an erection-causing drug directly into
their own
penis, without pain.
Dr. Neil Gesundheit/Vivus Corp.: "OUR SYSTEM IS VERY SIMPLE.
INVOLVES INSERTING A VERY SMALL APPLICATOR INTO THE DISTAL
OR FAR PART OF THE PENIS, JUST INTO THE OPENING, AND LEAVING
A VERY SMALL PELLET OF MEDICATION THERE THAT DISSOLVES, IS
ABSORBED LOCALLY, AND ACTS AS A VASAL DILATOR AND BEGINS
THE ERECTION PROCESS."
In the past, a similar drug would have had to have been injected into the
penis with
a needle, a painful and unpleasant process. The Vivus drug pellet, on the
other
hand, is 5 to 10 times smaller than an eyedrop. The company says it's system
restores erections in up to 65 percent of men suffering from impotence.
Gesundheit: "WITHIN ABOUT 5 TO 10 MINUTES, THE PATIENT
ACHIEVES THE BEGINNING OF AN ERECTION, AND A FULL ERECTION
USUALLY OCCURS WITHIN 10 TO 15 MINUTES. THE ERECTION IN OUR
HANDS LASTS BETWEEN 40 AND 60 MINUTES."
Up until only a decade ago, doctors were telling most men who complained of
impotence, it's all in your head. Now they know where the problem really is.
Dr. Nancy Snyderman: "IT'S BEEN VERY SIMPLE UP UNTIL NOW TO SAY,
OH IT'S IN YOUR HEAD, BECAUSE WE HAVEN'T UNDERSTOOD IT. BUT
WE DO KNOW THERE'S A VERY COMPLICATED PROCESS INVOLVING
NERVES AND THE BLOOD VESSELS DILATING TO ALLOW THE BLOOD
TO GET INTO THE PENIS. AND IN MEN WHO ARE IMPOTENT, THOSE
BLOOD VESSELS DON'T SEEM TO DILATE CORRECTLY. THIS
MEDICATION OPENS UP THOSE BLOOD VESSELS AND ALLOWS
BLOOD TO GET THROUGH."
The Vivus system is waiting for FDA approval. The company hopes to have it
commercially available in 1997. In San Francisco, Tony Russomanno, Channel 5
Eyewitness News. <