Discussion
Autoimmune oophoritis is a rare clinicopathologic entity
of which approximately 30 cases have been described. Most patients present
in their reproductive years, typically with oligomenorrhea or amenorrhea,
infertility, mutiple follicle cyts, and abnormal uterine bleeding due to
estrogenic manifestations and inadequate progesterone secretion.
Patients may have humoral antibodies or cellular-mediated
immune reactions against a variety of antigens usually associated with
steroid producing cells.
The histopathological hallmark is a dense infiltrate
of small lymphocytes and polyclonal plasma cells.
Message