MASOOD AHAMMED.M _____________________________________________________________ AU-KBC Research Centre, MIT campus of Anna University,Chennai, India. 600044 e-mail : masood@au-kbc.org, masoodahammed@yahoo.com Phone : 91 44 2223 2711 / 4885 Fax 1034 _____________________________________________________________ ----------------- Academic Profile ----------------- MS (by Research) Life Sciences and Bioinformatics (June 2001-Present) AU-KBC Research Centre, Anna University,(www.au-kbc.org) Thesis : Modeling of myogenic response in smooth muscle cells of cerebral arteries CGPA 8.0 / 10.0 M.Tech Biotechnology ( December 1999 - May 2001 ) Jadavpur University,Calcutta, India. Project : Studies on Production of beta- Lactamase by recombinant E.coli DH5 in a Bioreactor Percentage -76 ; Second Rank B.Tech Dairy Science & Technology ( April 1999 ) Kerala Agricultural University, India. OGPA - 8.5 / 10.0 -------------------- Research experience -------------------- June 2001 - present, Research Scholar,AU-KBC Research Centre of Anna University,Chennai Project : Modeling vascular smooth muscle cells Supervisor :Dr.S.V.Ramanan (Wellcome Senior International Fellow) Abstract Vascular smooth muscle cells form the basis for myogenic response of smooth muscle in cerebral arteries,an important example of co-ordinated response in tissues. It refers to the acute reaction of a blood vessel to a change in trans-mural pressure. Blood vessel contracts when intra vascular pressure is elevated and conversely dilates on reduced in pressure. As compared to cardiac cells,there has been little quantitative modeling of smooth muscle. The steady state model that we have developed includes contributions from voltage dependent L - type calcium channel, calcium induced ca release from SR, membrane dependent ca released by iP3, ca diffusion and buffering, ca extrusion pumps & exchangers and ca dependent maxi -K channels.Dynamics of other important ions are also included in the model through delayed rectifier K+ channels, inward rectifier K+ channels , Na-K pumps, Na-Ca exchangers and background currents. Dec 2000 - May 2001 Department of Life Sciences & biotechnology, Jadavpur University. M.Tech (Biotechnology) Project on "Studies on Production of beta- Lactamase by recombinant E.coli DH5 in a Bioreactor " Supervisor: Dr.Joydeep Mukherjee Abstract Characteristics of growth and synthesis of plasmid encoded protein were studied for strains of recombinant E.coli DH 5 alpha that carried the beta Lactamase gene in pUC 19. Experiments in minimal medium ( M9 ) with different carbon source were conducted in shake flasks and bioreactor (Chemap 3.5 L).Optimization of the bioreactor parameters and analysis of dissolved oxygen utilization and biomass production were also studied. -------- Training -------- S* online Bioinformatics certificate course (Feb 2003-June 2003) by S*Life Science Informatics Alliance (www.s-star.org) Indian Institute of Spices Research,( May 2000 - June 2000 ) Department of Plant Biotechnology Summer Training Project on " Tissue Culture of Spices " Defense Food Research Laboratory,Mysore.( Oct 01 - Nov 01 ) Food analysis and quality Assurance ----------- Publication ----------- Development of a Computer Program to predict the b-Lactamase Activity on the Basis of Ampicillin Fluorescence Values`, H. V. Rao, A. M. Masood and J.Mukherjee. Journal of Fluorescence, Vol. 12, No. 2, June 2002 ------------- Presentations ------------- 'Kinetic kit of Genesis software ' in the " Mini Workshop on Theoretical Biology: E cell,Virtual cell and Genesis" held at Institute of Mathematical Sciences,Chennai (22 - 28 June 2002) ----------- Fellowships ----------- AU-KBC Research Centre Fellowship for MS(By Research)June 01-present Qualified in All India Combined Biotechnology Entrance Examination 1999 conducted by Jawaharlal Nehru University and Department of Biotechnology (Govt. of India) for admission & Fellowship to pursue M.Tech Biotechnology at Jadavpur University. (Dec 1999- June 2001) Qualified in Graduate Aptitude Test for Engineering (GATE-2001) in Life Sciences conducted by IITs for Ministry of Human Resources Development (Govt. of India). Selected for the Summer Research program 2001 at Center for DNA finger printing and Diagnostics, Hyderabad for two months. ---------------- Technical skills ---------------- Electro physiology : Patch Clamping Bio Reactor Technology : Handling lab scale fermentors Microbiology : Isolation and maintance of culture. Molecular Biology : Expression and purification of recombinant protein in E.coli, PCR etc --------------- Computer skills --------------- Programming Languages : C, Perl, Shell Script Operating systems : GNU / Linux, DOS and Windows NT 4.0 Relational Databases : MySql Bioinformatics Packages : EMBOSS, Genesis , Virtual Cell --------------------------- Extra curricular activities --------------------------- National Cadet Corps 'C' Certificate Holder, National Service Scheme Class Leader. Participated in East India Zone Inter University arts festival Representing Jadavpur University for cartooning, poster making & college making.Won prizes in Quiz competitions ---------------- Personal details ---------------- Date of Birth : 05 Feb 1977 Sex : Male Languages : English,Hindi,Malayalam,Urdu,Tamil Marital Status : Married -------- Referees -------- Dr. S.V. Ramanan, Wellcome International Senior Fellow; Professor, Gopala Iyer Chair, AU-KBC Research Centre,MIT campus of Anna University, Chennai,India. ramanan@au-kbc.org Dr. Joydeep Mukherjee, Lecturer, Dept Life Sciences & Biotechnology, Jadavpur University, Calcutta 32, India joymukherjee@vsnl.com