| Symptoms |
| Symptoms for Cryoglobulinemia vary depending on which type one has. While some symptoms from one type may overlap into another, other symprtoms can be distinct to one type. Type I: This type is often without symptoms, however, one may be inflicted with purpura, Raynaud's Phenomenon, ischemic ulcers and livdeo reticularis. Vasculitis is *very* rare in Type I. Type II (Mixed): Raynaud's Phenomenon, purpura, vasculitis, joint pain, muscle pain and weakness, fatigue, hepatomegaly, splenomegaly, glomerulonephritis, pericarditis, rheumatoid factor, itchy skin. Essential (EMC): Joint pain and swelling, fatigue, muscle pain and weakness, vasculitis, splenomegaly, poor appetite leading to weight loss. |