Sacha
Russian: diminutive form, or nickname of Alexander

Sagi
Aramaic: the strong and mighty one

Sal
Latin: salt
Old English: a willow
(Sale)

Salim
Swahili: peace
(Salem)

Salvador
Latin: to be saved, or the Savior
(Sal, Sallie, Salvadore, Salvator, Salvatore)

Samson
Hebrew: being as bright as the light of the sun
(Sam, Sammy, Sonny, Sonnie)

Samuel
Hebrew: the answer to prayers to God
(Sam, Sammie, Sammy)

Samuru
Japanese: he whose name is God

Santos
Spanish: belonging to or coming from the saints
(Sancho, Sanchez, Sanches, Saint, Sanche, Santo, Santi)

Sanyu
Ugandan: happiness

Sargent
Latin: a military man
(Sarj, Sarge, Seargent)

Saul
Hebrew: asked for
(Saulo)

Sawyer
Middle English: woodcutter

Saxon
Old English: he who bears arms, the swordsman
(Sax)

Schuyler
Dutch: learned man, or scholar
(Sky, Skye, Skyler)

Scott
Old English: from Scotland, or Scottish people
(Scot, Scotty, Scottie)

Sean
Irish: form of John
(Shawn, Shaun, Shane)

Sebastian
Greek: majestic
(Bastian, Bastien, Seb, Sebastien, Sebastiano)

Selby
Teutonic: he who lives by the manor's farm
(Shelby)

Selig
Teutonic: being blessed and possessed of holiness
(Zelik)

Sempala
Ugandan: a child of riches, born during prosperity

Serge
Latin: servant, or attendant to nobility
(Sergei, Sergio, Sergi, Sergiu)

Seth
Hebrew: the appointed one, or compensation

Seymour
Old French: form of Maurice
(Morey, Morrie, Morry, Seymore)

Shakir
Arabic: greatful, full of thankfulness

Shamus
Irish: form of James
(Seamus)

Shane
Irish: form of John
(Shaine, Shayn, Shayne)

Shannon
Gaelic: little wise one
(Shannan, Shanon, Shanen)

Shaun
Irish: form of John
(Seamus, Sean, Shamus, Shane, Shawn)

Shea
Gealic: fairy place, or a man from the fairy grotto
(Shay, Chay)

Sheehan
Celtic: little, peaceable, or the peacemaker

Shelby
Anglo-Saxon: the farm near the cliff
(Shel, Shell, Shelly, Shelley)

Shelley
Anglo-Saxon: the farm on the ridge
(Shell, Shelly, Shelby, Sheldon, Shelton)

Sherman
Anglo-Saxon: clothcutter
(Sherm, Shermy, Shermie)

Shing
Chinese: victory, or the victorious one

Shlomo
Hebrew: peaceful, peace seeking
(Shelomo, Solomon)

Sidney
Old French: derived from St. Denis
(Sid, Sy, Syd, Sydney)

Siegfried
German: peaceful victory, or peacefully victorious
(Sig, Siggy, Sigfrid, Sigfried)

Simon
Hebrew: he who has heard
Greek: snub-nosed
(Si, Silas, Silm, Simeon, Shimon, Simpson, Syman, Shimon, Simpson, Syman, Symon, Sy)

Sinai
Hebrew: the desert of clay
(Si, Sy)

Skip
Old Norse: a ship owner
(Skipper, Skippy)

Sloan
Celtic: warrior
(Sloane)

Smith
Old English: blacksmith
(Smitty)

Solomon
Hebrew: peaceful
(Salomon, Salman, Selman, Shalom, Sholom, Sueleiman, Zalman, Zelman)

Son
Native American: star

Sook
Korean: light

Spark
Middle English: happy go lucky
(Sparky)

Spencer
English: steward, or shop keeper
(Spence)

Stacy
Latin: fruitful, or good companion
(Stace, Stacey, Stacie)

Stanislaus
Slavic: glorious stand
(Stan, Stanislas, Stanislaw, Stanislav, Stanislao, Estanislau)

Stanley
English: stony field
(Stan, Stanly, Stash, Stosh)

Stavros
Greek: crowned with laurel leaves

Stephen
Greek: garland, or crown
(Stefan, Stefen, Steve, Stevie, Steven, Stefano, Etienne, Esteban, Estevan, Stephanas, Stepan, Stepka)

Sterling
English: of highest quality
(Stirling)

Stuart
Anglo-Saxon: keeper of the estate
(Stu, Steward, Stewart, Stuward, Stuwart, Stew)

Sullivan
Irish: black-eyed
(Sully)

Sumner
Latin and French: summoner

Sutton
Old English: village to the south

Sven
Swedish: youth
(Svend, Swen)

Swithin
Old English: strong
(Swithun)

Sylvester
Latin: woods
(Silvester, Sy, Sly, Silas)