Michigan State Route 53 is a north-south highway in Western Macomb County. From Sterling Heights to near Washinton, this is a expressway. MI St Rt 53 passes through the following towns in Macomb County. Warren Center Line Sterling Heights Utica Shelby Township MI St Rt 53 is not multi-plexed in Macomb County. MI St Rt 53 intersects the following highways in Macomb County. Michigan State Route 102, at Warren. Interstate 696, at Center Line. Michigan State Route 59, at Utica.