| ACROSS | DOWN |
| 1 These nonspecific defenses include the epidermis | 2 The nonspecific defense immunological ____________ is performed by NK cells |
| 4 This follows inflammation | 3 These nonspecific defenses include microglia and neutrophils |
| 7 A nonspecific defense; 11 proteins that help antibodies by attracting phagocytes and easing their work, rupturing cells and promoting inflammation | 5 The nonspecific defense activated when torn connective tissue induces mast cells to secrete heparin and histamine |
| 10 Large phagocytes derived from monocytes | 6 Circulating agents that serve to induce the nonspecific defense fever |
| 11 These nonspecific defenses are proteins generated by lymphocytes, macrophages and infected tissue that interfere with viral replication and stimulate macrophages and NK cells | 8 Neutrophils and eosinophils, collectively |
| 12 A chemical messenger released by tissue to coordinate local activity | 9 Sensing a chemical gradient and moving toward or away accordingly |