| ACROSS | DOWN |
| 4 Second trait of immunity; involves the construction of lymphocytes with millions of different antigen receptors | 1 These B cell daughter cells generate antibodies that target the activating antigen |
| 6 Immunoglobulins responsible for blood type cross reactions and binds to IgG resistant pathogens | 2 A kind of acquired immunity following exposure to an antigen |
| 7 Immunoglobulins binding antigens to B cells | 3 T cells that release cytokines to stimulate cell and antibody mediated immune response and coordinate specific and nonspecific defenses |
| 9 Third trait of immunity; speeds next counterattack with types of B and T cells named for this trait | 5 Immunoglobulins responsible for resisting viruses, bacteria, bacterial toxins (80% of total immunoglobulins) |
| 12 Besides virus-infected cells, this kind of cell manifests the MHC-antigen complex that triggers T cell differentiation | 6 A kind of immunity for which previous exposure is irrelevant |
| 13 It can be mediated by cells or antibodies | 8 These T cells begin to secrete suppression factors after the other kinds of T cells have already commenced function |
| 17 Killer T cells use this to outright poison the targeted cell | 10 Reserve T cells that lay in wait for the next incursion of the antigen |
| 22 First trait of immunity; made possible by antigen recognition | 11 Reserve T cells that lay in wait for the next incursion of the antigen |
| 23 These are mostly activated by helper T cells | 14 Fourth trait of immunity; destroying T and B cells with self antigen receptors |
| 15 Killer brand of T cells that searches out and destroys antigen-bearing targets | |
| 16 Killer T cells use cytokines to trigger this so the targeted cell kills itself | |
| 18 Killer T cells use this to puncture the targeted cell's membrane | |
| 19 Immunoglobulins interacting with pathogens before they enter tissues | |
| 20 A kind of acquired immunity following exposure to someone else's antibodies | |
| 21 Immunoglobulins augmenting the immune response |