Buttock pain

Ulcerations and mucositis of the mouth, tongue, and pharynx can occur. buttock pain Psoriasis arthritis. If a mild mucocutaneous eruption occurs, therapy should be interrupted. If the eruption abates, therapy can be restarted at a 10-15mg weekly, titrating upwards to 50mg weekly with careful monitoring for further rash. Up to 10% of patients have mild proteinuria due to a gold induced membranous glomerulonephropathy that can progress to the nephrotic range. buttock pain Complex regional pain syndrome. Patients with a positive urine dipstick for protein should be evaluated with a 24-hour urine collection and gold therapy stopped if proteinuria exceeds 500mg/24 hours. Mild proteinuria generally resolves with the cessation of therapy. Occasionally patients will have isolated microscopic hematuria on gold therapy. buttock pain Head pain. If monitored closely gold therapy can be continued but other causes of hematuria must be excluded. Immune thrombocytopenia, granulocytopenia, and aplastic anemia occur uncommonly but are absolute indications for cessation of gold therapy. Myochrysine, and less often Solganal, can produce a nitritoid reaction (flushing, dizziness, or fainting) occurring immediately after the gold injection. Rarely, there is a paradoxical increase in musculoskeletal pain that requires discontinuation of treatment. (top of section)Immunosuppressive and other cytotoxic Agents The most commonly used drugs are azathioprine (Imuran), cyclophosphamide (Cytoxan) and cyclosporin A. Because the potential of high toxicity, these agents are utilized for life-threatening extra-articular manifestations or severe articular disease refractory to other therapy. It is recommended that these agents be used under the direction of a rheumatologist. Azathioprine is a purine analog that can cause severe bone marrow suppression particularly in patients with renal insufficiency or when used concomitantly with allopurinol or ACE inhibitors. Increased risk of secondary malignancy due to azathioprine is controversial. Cyclophosphamide is an alkylating agent with serious toxicity's including bone marrow suppression, hemorrhagic cystitis, premature ovarian failure, infection and secondary malignancy particularly an increased risk of bladder cancer.

Buttock pain



Symptoms || Treatment-for-pain-sciatic-nerve || Early symptoms of arthritis || Low back pain exercise