Jonathan has open-heart surgery; Another person is brought back to life using the same serum that Adam used; Adam's fate is revealed.

What's up with Jonathan: The doctors give Jonathan a heart check-up and tell him that he needs a triple bypass operation. Jonathan is reluctant but when Clark tells him he wants him to do it, Jonathan agrees.

What's up with Clark: While Clark's at the hospital he sees his friend Garrett Davis. Garrett's brother Vince is in need of a liver transplant and isn't doing well. Vince dies later that day and his body is flown to Metropolis. Garrett's parents died when he was young and he has no family in the States, so the Kents offer their couch to him for the night until his Uncle can fly in from Germany. That night Garrett gets the news that his brother was cremated, which is a shock because he was suppose to be buried next to his mom and dad.

What's up with Vince: Vince's body is flow to Dr. Teng's lab in Metropolis. When he arrives she injects him with a large needle and he miraculously comes back to life. As Clark tries to comfort Garrett at the farm, Vince walks in! He says he woke up at a lab, but can't remember anything else. Garrett is elated and Clark shocked, but as the two ask Vince questions, he begins to bleed from his eye (just like Adam did) and he collapses. The doctors at the hospital are perplexed and say they can't save him, which drives Garrett into a rage, and he runs away.

How it ends: Clark runs into Lana outside the hospital, she tells him that Vince's situation sounds identical to Adams. Garrett returns to the hospital with a bomb strapped to his chest. He demands that the doctors give Vince a liver transplant immediately or he'll kill everyone. Martha, Pete and Lana are trapped, and Jonathan is already in the operating room. Clark has teamed up with Chloe to try and track down the lab where Vince was resurrected. Chloe has also been working with Lex to find Adam. When Clark gets to the lab, he hears Lex talking to Dr. Teng. He hears that the serum is the same that was used on Adam, and he uses his super speed to steal it.

When Clark returns to the hospital he convinces the sheriff to let him talk to Garrett... Garrett agrees to let the hostages go if Clark comes in with the serum, which Clark has told him will save his brother's life. As Martha comes out, she tells Clark to be careful, the bomb has been laced with meteor rock so he won't be able to use his powers. Meanwhile, the sheriff tells a sniper that if he gets the shot, take Garrett out. Garrett gets the serum from Clark and tells the doctor to inject it into Vince. As Garrett holds the serum to his chest it bubbles and turns red (the same effect kryptonite has on Clark's blood!). The doctor injects the serum, but nothing happens. Garrett impatiently tells the doctor it's not working and to use Jonathan's liver, telling Clark he'll still have a mom, but he has no one if Vince dies. As they walk to the room Jonathan's in, the sniper gets a clear shot and kills Garrett, just before he dies, he hits the detonator. Clark uses his speed to get a lead jacket, put it over the bomb and run it to a deserted area where it explodes.

Teng tells Lex later that she's kept Adam alive and has hidden him from Lionel in the basement. She shows him to Lex and tells him he's deteriorating, that the serum hasn't been perfected and doesn't seem to be able to sustain reanimated life. Jonathan's surgery is a success and he's sent home. Clark tells him he believes that Lionel is using the serum, which is made from Clark's blood, to bring people back to life.