Color, Closed-captioned, Widescreen
Number of discs: 2
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| Audrey Tautou | Amélie Poulain |
| Mathieu Kassovitz | Nino Quincampoix |
| Rufus | Raphaël Poulain, Amélie's Father |
| Lorella Cravotta | Amandine Poulain |
| Serge Merlin | Raymond Dufayel aka Glass Man |
| Jamel Debbouze | Lucien |
| Clotilde Mollet | Gina, Two Windmills waitress |
| Claire Maurier | Suzanne, Owner Two Windmills bar |
| Isabelle Nanty | Georgette, Two Windmills Cigarette counter girl |
| Dominique Pinon | Joseph |
| Artus de Penguern | Hipolito, The Writer |
| Yolande Moreau | Madeleine Wells, concierge |
| Urbain Cancelier | Collignon, The Grocer |
| Maurice Bénichou | Bretodeau, The Box Man |
| Michel Robin | Mr. Collignon |
| Andrée Damant | Mrs. Collignon |
| Claude Perron | Eva, The Strip Teaser |
| Armelle | Philomène |
| Ticky Holgado | Man in photo (who describes Amelie to Nino) |
| Kevin Fernandes | Bretodeau as a Child |
| Flora Guiet | Amélie (6 Years Old) |
| Amaury Babault | Nino (As a Child) |
| André Dussollier | Narrator/Récitant |
| Eugène Berthier | Eugene Koler |
| Marion Pressburger | Credits Helper |
| Charles-Roger Bour | The Urinal Man |
| Luc Palun | Amandine's Grocer |
| Fabienne Chaudat | Woman in Coma |
| Dominique Bettenfeld | The Screaming Neighbor |
| Jacques Viala | The Customer Who Humiliates His Friend |
| Fabien Béhar | The Humiliated Customer |
| Jonathan Joss | The Humiliated Customer's Son |
| Jean-Pierre Becker | The Bum |
| Jean Darie | The Blind Man |
| Thierry Gibault | The Endive Client |
| François Bercovici | His Buddy |
| Franck Monier | Dominique Bredoteau Kid |
| Guillaume Viry | The Vagrant |
| Valérie Zarrouk | Dominique Bredoteau Woman |
| Marie-Laure Descoureaux | The Dead Man's Concierge |
| Sophie Tellier | Aunt Josette |
| Gérald Weingand | The Teacher |
| François Viaur | The Bar Owner |
| Paule Daré | His Employee |
| Marc Amyot | The Stranger |
| Myriam Labbé | The Tobacco Buyer |
| Jean Rupert | Nasal operation man |
| Frankie Pain | The Newsstand Woman |
| Julianna Kovacs | Grocer's Client |
| Philippe Paimblanc | Train Ticket Taker |
| Mady Malroux | One of the Twins |
| Monette Malroux | One of the Twins |
| Robert Gendreu | Cafe Patron |
| Valériane de Villeneuve | The Laughing Woman |
| Isis Peyrade | Samantha |
| Raymonde Heudeline | Phantom Train Customer |
| Christiane Bopp | Woman by the Merry-Go-Round |
| Thierry Arfeuillères | Statue Man |
| Jerry Lucas | The Sacré-Coeur Boy |
| Patrick Paroux | The Street Prompter |
| François Aubineau | The Concierge's Postman |
| Philippe Beautier | Poulain's Postman |
| Karine Asure | Pretty Girl at Appointment |
| Régis Iacono | Félix L'Herbier |
| Franck-Olivier Bonnet | Palace Video |
| Alain Floret | The Concierge's Husband |
| Jean-Pol Brissart | The Postman |
| Frédéric Mitterrand | Himself |
| Rudy Galindo | Himself |
| Sam 'Peg Leg' Jackson | Himself |
| Tchéky Karyo | Man on photo in Nino's photo album |
| Jean-Michel Larqué | Himself/TV commentator |
| Thierry Roland | Himself/TV commentator |
| Jacques Thébault | Voice-Over |
| Manoush | Nymphomaniac woman |
| Sister Rosetta Tharpe | Herself |
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