Color, Closed-captioned, Widescreen, DTS Surround Sound
Full Length Commentary by directors Albert and Allen Hughes, Screenwriter Rafael Yglesias, Cinematographer Peter Deming, and Actor Robbie Coltrane
Alternate Ending and over 20 deleted scenes with optional commentary by Albert Hughes
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| Johnny Depp | Inspector Fred Abberline |
| Heather Graham | Mary Kelly |
| Ian Holm | Sir William Gull |
| Robbie Coltrane | Sergeant Peter Godley |
| Ian Richardson | Sir Charles Warren |
| Jason Flemyng | Netley, the Coachman |
| Katrin Cartlidge | Dark Annie Chapman |
| Terence Harvey | Benjamin 'Ben' Kidney |
| Susan Lynch | Liz Stride |
| Paul Rhys | Dr. Ferral |
| Lesley Sharp | Kate Eddowes |
| Estelle Skornik | Ada |
| Nicholas McGaughey | Officer Bolt |
| Annabelle Apsion | Polly |
| Joanna Page | Ann Crook |
| Mark Dexter | Albert Sickert/Prince Edward Albert Victor |
| Danny Midwinter | Constable Withers |
| Samantha Spiro | Martha Tabram |
| David Schofield | McQueen |
| Bryon Fear | Robert Best |
| Peter Eyre | Lord Hallsham |
| Cliff Parisi | Mac Bartender |
| Sophia Myles | Victoria Abberline |
| Ralph Ineson | Gordie |
| Amy Huck | Gull's Maid |
| Rupert Farley | Doss Landlord |
| Donald Douglas | Hospital Director |
| John Owens | Marylebone Governor |
| Liz Moscrop | Queen Victoria |
| Ian McNeice | Robert Drudge |
| Steve John Shepherd | Special Branch Constable |
| Al Ashton | Stonecutter |
| Poppy Rogers | Alice Crook |
| Bruce Byron | Ann Crook's Father |
| Melanie Hill | Ann Crook's Mother |
| Andy Linden | Carpenter |
| David Fisher | Carpenter/Letter Writer |
| Gary Powell | Constable #1 |
| Steve Chaplin | Constable #2 |
| Vincent Franklin | George Lusk |
| Louise Atkins | Bold Hooker |
| Anthony Parker | John Merrick |
| James Greene | Masonic Governor |
| Dominic Cooper | Constable #3 |
| Carey Thring | Police Photographer |
| Vladimir Kulhavy | Rag & Bone Man |
| Graham Kent | Records Clerk |
| Rupert Holliday-Evans | Sailor |
| Simon Harrison | Thomas Bond |
| Paul Moody | Young Doctor |
| Glen Berry | Young Labourer |
| Charlie Parish | Labourer #2 |
| Gerry Grennell | Funeral Minister/Letter Writer |
| Roger Frost | Sidewalk Preacher |
| Stephen Milton | Medical Student |
| Tony Tang | Opium Den Owner |
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