Age is an issue of mind over matter. If you don't mind, it doesn't matter.

Mark Twain

In zootomy and dermatology, skin is an organ of the integumentary system composed of a layer of tissues that protect underlying muscles and organs. As the interface with the surroundings, it plays the most important role in protecting against pathogens. Its other main functions are insulation and temperature regulation, sensation and vitamin D and B synthesis.

Skin has pigmentation, provided by melanocytes, which absorbs some of the potentially dangerous radiation in sunlight. It also contains DNA repair enzymes which reverse UV damage, and people who lack the genes for these enzymes suffer high rates of skin cancer. One form predominantly produced by UV light, malignant melanoma, is particularly invasive, causing it to spread quickly, and can often be deadly. Human skin pigmentation varies among populations in a striking manner. This has sometimes led to the classification of people on the basis of skin color. See the article on human skin color.

Mammalian skin often contains hairs, which in sufficient density is called fur. The hair mainly serves to augment the insulation the skin provides, but can also serve as a secondary sexual characteristic or as camouflage. On some animals the skin is very hard and thick, and can be processed to create leather. Reptiles and fish have hard protective scales on their skin for protection, and birds have hard feathers, all made of tough β-keratins. Amphibian skin is not a strong barrier to passage of chemicals. A frog sitting in an anesthetic solution will quickly go to sleep.

The skin is often known as "the largest organ in the human body". This applies to exterior surface, as it covers the body, appearing to have the largest surface area of all the organs. Moreover, it applies to weight, as it weighs more than any single internal organ, accounting for about 15 percent of body weight. For the average adult human, the skin has a surface area of between 1.5-2.0 square metres, most of it is between 2-3 mm thick. The average square inch of skin holds 650 sweat glands, 20 blood vessels, 1000 melanocytes, and more than a thousand nerve endings.

The outermost epidermis is consists of stratified squamous epithelium with an underlying basement membrane. It contains no blood vessels, and is nourished by diffusion from the dermis. The main type of cells which make up the epidermis are keratinocytes, with melanocytes and Langerhans cells also present. The epidermis can be further subdivided into the following strata (beginning with the outermost layer): corneum, lucidum, granulosum, spinosum, basale. Cells are formed through mitosis at the innermost layers. They move up the strata changing shape and composition as they differentiate, inducing expression of new types of keratin genes. They eventually reach the corneum and become sloughed off (desquamation). This process is called keratinization and takes place within about 30 days. This layer of skin is responsible for keeping water in the body and keeping other harmful chemicals and pathogens out.

Blood capillaries are found beneath the epidermis, and are linked to an arteriole and a venule. Arterial shunt vessels may bypass the network in ears, the nose and fingertips.

The hypodermis is not part of the skin, and lies below the dermis. Its purpose is to attach the skin to underlying bone and muscle as well as supplying it with blood vessels and nerves. It consists of loose connective tissue and elastin. The main cell types are fibroblasts, macrophages and adipocytes (the hypodermis contains 50% of body fat). Fat serves as padding and insulation for the body.

The constantly peeling off dead cells of the epidermis mix with the secretions of the sweat and sebaceous glands and the dust found on the skin to form a filthy layer on its surface. If not washed away the dirt and dead skin slurry begins to decompose emitting a foul smell.

Functions of the skin are disturbed when it is dirty and it becomes more easily damaged. The release of antibacterial compounds decreases. Dirty skin is more prone to develop infections. Cosmetics should be used carefully because these may cause allergic reactions. Each season requires suitable clothing in order to facilitate the evaporation of the sweat. Sunlight, water and air play an important role in keeping the skin healthy.

If you take care of your skin, your skin will take care of you! But with all of the lotions, creams, and potions on the market, it can be difficult to know which product will work for you. Many products claim to remove wrinkles or heal dry skin. Others claim to contain expensive ingredients that they say will improve the effects of the product.

The first step to taking care of your skin is preventing damage. Sun, wind, pollutants, and simply aging can degrade the condition of your skin. Common complaints include dry and itchy skin, wrinkles, sagging, color changes, and age spots. There are steps that you can take to keep you skin looking and feeling its best.

Exercise, rest, and good nutrition lay the foundation for beautiful, healthy skin, inside and out. A proper diet is not only good for your overall health, it also helps to ensure that your skin will receive all of the vitamins, minerals, and nutrients that it needs to maintain and repair cells. Drinking purified water is another good way to keep your skin healthy. Water helps to hydrate the skin and move waste and nutrients through the system. It is very effective mixing a teaspoon or capful of Organic Apple Cider Vinegar in with your water. Do not drink Tap Water.

Dry skin is very common, especially with age. Older skin has fewer sweat and oil glands than younger skin. Dry skin may be caused by frequent baths, certain cosmetics or medications. But whatever the cause, there are ways to alleviate the itchiness associated with it. Avoid using harsh soaps when bathing, and if possible, cut back on the number of baths or showers each week. A sponge bath with warm water may help to clean and revive skin without stripping the skin of its valuable moisturizers.

A skin care routine does not have to be elaborate in order to be effective. But you should develop some kind of skin care routine based on your skin type, daily activities, and nutritional needs so that you can be sure you are taking the very best care of your skin. Following a daily skin care regime will also allow you to more closely evaluate your skin for abnormalities.

Wash your skin thoroughly on a daily basis to remove the dirt, debris, pollutants, and perspiration that accumulates on a daily basis. If you have dry or sensitive skin, use only warm water to wash your skin and use a mild natural cleanser every few days. If you have normal or oily skin, be sure to wash with a gentle cleanser on a daily basis. Be sure to brush your teeth before washing your face, as toothpaste residue can irritate sensitive facial skin.

Unless your skin is very oily, you will want to use a moisturizer everyday to keep your skin hydrated and healthy. Your skin needs moisturizer all year long as both the indoor winter heat, and summer sun can be equally damaging to your skin.

Acne, pimples, sunspots, age spots, wrinkles and other blemishes are skin conditions that plague people the world over. The global beauty industry already makes billions of dollars every year as women everywhere embark on quests to preserve (or achieve) a youthful, glowing appearance. Responding to this need, dermatologists, and other specialists continue to look for the best and safest possible treatments and formulations to combat skin ailments, the most common of which is acne.

For people seeking solutions to severe damage that has already been done to the skin, there are a number of treatments available ranging from chemical peels and dermabrasion to the latest and technologically advanced, computerized laser resurfacing. However, many people looking for skin repair are hesitant to try chemical or laser peels due to the painful procedure and long recuperation period they have to undergo. The results of these procedures however, are fantastic.

There are a lot of skin care products in the market today. Unlike before when a normal bar of soap was used for skin cleansing, cosmetic companies are now producing a wide variety of skin care treatments that can address various skin concerns. However, there are cases when treatments need to be more aggressive, especially for those who have aging or blemished skin. Most, if not all, of the over-the-counter products are topical in nature, meaning it only affects the epidermis or the outer layer of the skin. Aging or blemished skin needs to be treated down to the root of the problem to see definite changes.

Terms and definitions

Acne

• An inflammatory disease of the sebaceous glands and hair follicles of the skin that is marked by the eruption of pimples or pustules, especially on the face.

Bacteria

• Microscopic unicellular prokaryotic organisms characterized by the lack of a membrane-bound nucleus and membrane-bound organelles.

Dermis

• The sensitive connective tissue layer of the skin located below the epidermis, containing nerve endings, sweat and sebaceous glands, and blood and lymph vessels.

Epidermis

• The outer, protective, nonvascular layer of the skin of vertebrates, covering the dermis.

Hypodermis

• A subcutaneous layer of loose connective tissue containing a varying number of fat cells.

Pimples

• A small swelling of the skin, usually caused by acne; a papule or pustule.

Ultraviolet radiation

• Invisible electromagnetic radiation between visible violet light and X rays.

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